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Synthese und Charakterisierung von Plazenta Chondroitin Sulfat (PlCSA) - Targeting Lipid - Polymer Nanopartikel

Article DOI: 10.3791/58209-v • 05:55 min • September 18th, 2018
September 18th, 2018 •
*1, *2,3, 2, 1
1Laboratory for Reproductive Health, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences (CAS), 2Guangdong Key Laboratory of Nanomedicine, CAS Key Lab for Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences (CAS), 3Department of Chemistry, Guangdong Medical University
* These authors contributed equally

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Hier präsentieren wir ein Protokoll für die Synthese von Plazenta Chondroitinsulfat A Bindung Peptid (PlCSA-BP)-konjugiert Lipid-Polymer Nanopartikel über einstufigen Beschallung und Bioconjugate Techniken. Diese Partikel bilden ein neuartiges Instrument für die gezielte Bereitstellung von Therapeutika, die meisten menschlichen Tumoren und Plazenta Trophoblasten zur Behandlung von Krebserkrankungen und plazentare Störungen.

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Cancer Research Ausgabe 139 Plazentare Chondroitinsulfat A Lecithin PLGA Nanopartikel Oberfläche Konjugation Drug-Delivery Choriocarcinoma Plazenta targeting Tumor targeting
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