Presented here is a protocol for the fabrication of iron oxide nanoparticle-shelled microbubbles (NSMs) through self-assembly, synergizing magnetic, acoustic, and optical responsiveness in one nanotherapeutic platform for magnetic hyperthermia and photothermal combination cancer therapy.
Yin, Y., Wang, S., Hu, D., Cai, J., Chen, F., Wang, B., Gao, Y. Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy. J. Vis. Exp. (159), e61208, doi:10.3791/61208 (2020).