Birgit Schilling Biography Publications JoVE Articles Birgit Schilling has not added a biography. If you are Birgit Schilling and would like to personalize this page please email our Author Liaison for assistance. Publications Cytotrophoblast Extracellular Vesicles Enhance Decidual Cell Secretion of Immune Modulators Via TNF-alpha Development (Cambridge, England). Aug, 2020 | Pubmed ID: 32747437 Translational Control of One-carbon Metabolism Underpins Ribosomal Protein Phenotypes in Cell Division and Longevity ELife. May, 2020 | Pubmed ID: 32432546 The Power of Proteomics to Monitor Senescence-associated Secretory Phenotypes and Beyond: Toward Clinical Applications Expert Review of Proteomics. Apr, 2020 | Pubmed ID: 32425074 Abundances of Transcripts, Proteins, and Metabolites in the Cell Cycle of Budding Yeast Reveal Coordinate Control of Lipid Metabolism Molecular Biology of the Cell. 05, 2020 | Pubmed ID: 32129706 Skyline for Small Molecules: A Unifying Software Package for Quantitative Metabolomics Journal of Proteome Research. Apr, 2020 | Pubmed ID: 31984744 Activating Transcription Factor 4 (ATF4) Promotes Skeletal Muscle Atrophy by Forming a Heterodimer with the Transcriptional Regulator C/EBPβ The Journal of Biological Chemistry. Feb, 2020 | Pubmed ID: 31953319 A Proteomic Atlas of Senescence-associated Secretomes for Aging Biomarker Development PLoS Biology. Jan, 2020 | Pubmed ID: 31945054 Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species Scientific Reports. Oct, 2019 | Pubmed ID: 31659173 Dietary Sugars Alter Hepatic Fatty Acid Oxidation Via Transcriptional and Post-translational Modifications of Mitochondrial Proteins Cell Metabolism. Oct, 2019 | Pubmed ID: 31577934 Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect Against AKI Journal of the American Society of Nephrology : JASN. Dec, 2019 | Pubmed ID: 31575700 SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells Cell Reports. Sep, 2019 | Pubmed ID: 31553904 Accumulation of "Old Proteins" and the Critical Need for MS-based Protein Turnover Measurements in Aging and Longevity Proteomics. Aug, 2019 | Pubmed ID: 31408259 Post-translational Protein Acetylation: An Elegant Mechanism for Bacteria to Dynamically Regulate Metabolic Functions Frontiers in Microbiology. 2019 | Pubmed ID: 31354686 High-Resolution Mass Spectrometry to Identify and Quantify Acetylation Protein Targets Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 31087289 Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation Molecular Cell. 05, 2019 | Pubmed ID: 31000437 Correction for Christensen Et Al., "Identification of Novel Protein Lysine Acetyltransferases in Escherichia Coli" MBio. 04, 2019 | Pubmed ID: 30967468 JNK Modifies Neuronal Metabolism to Promote Proteostasis and Longevity Aging Cell. 06, 2019 | Pubmed ID: 30810280 Global Lysine Acetylation in Results from Growth Conditions That Favor Acetate Fermentation Journal of Bacteriology. 05, 2019 | Pubmed ID: 30782634 Temporal Dynamics of Liver Mitochondrial Protein Acetylation and Succinylation and Metabolites Due to High Fat Diet And/or Excess Glucose or Fructose PloS One. 2018 | Pubmed ID: 30586434 Identification of Novel Protein Lysine Acetyltransferases in Escherichia Coli MBio. 10, 2018 | Pubmed ID: 30352934 Identifying Ubiquitinated Proteins and Aggregates Aging. 10, 2018 | Pubmed ID: 30335616 Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves MTOR Malonylation Cell Metabolism. 12, 2018 | Pubmed ID: 30146486 Simultaneous Quantification of the Acetylome and Succinylome by 'One-Pot' Affinity Enrichment Proteomics. 09, 2018 | Pubmed ID: 30035354 Removing 4E-BP Enables Synapses to Refine Without Postsynaptic Activity Cell Reports. 04, 2018 | Pubmed ID: 29617653 Protein Turnover in Aging and Longevity Proteomics. Mar, 2018 | Pubmed ID: 29453826 An Acetylatable Lysine Controls CRP Function in E. Coli Molecular Microbiology. Jan, 2018 | Pubmed ID: 29105190 Ancient Regulatory Role of Lysine Acetylation in Central Metabolism MBio. Nov, 2017 | Pubmed ID: 29184018 Characterization of Inner and Outer Membrane Proteins FromStrains LVS and Schu S4 and Identification of Potential Subunit Vaccine Candidates MBio. Oct, 2017 | Pubmed ID: 29018123 Multi-laboratory Assessment of Reproducibility, Qualitative and Quantitative Performance of SWATH-mass Spectrometry Nature Communications. 08, 2017 | Pubmed ID: 28827567 PIQED: Automated Identification and Quantification of Protein Modifications from DIA-MS Data Nature Methods. Jun, 2017 | Pubmed ID: 28661500 Identification and Characterization of AckA-dependent Protein Acetylation in Neisseria Gonorrhoeae PloS One. 2017 | Pubmed ID: 28654654 MSstatsQC: Longitudinal System Suitability Monitoring and Quality Control for Targeted Proteomic Experiments Molecular & Cellular Proteomics : MCP. Jul, 2017 | Pubmed ID: 28483925 Clinical Applications of Quantitative Proteomics Using Targeted and Untargeted Data-independent Acquisition Techniques Expert Review of Proteomics. 05, 2017 | Pubmed ID: 28436239 Generation of High-Quality SWATHAcquisition Data for Label-free Quantitative Proteomics Studies Using TripleTOFMass Spectrometers Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28188533 Vitamin D Promotes Protein Homeostasis and Longevity Via the Stress Response Pathway Genes Skn-1, Ire-1, and Xbp-1 Cell Reports. 10, 2016 | Pubmed ID: 27783938 Stable Nuclear Expression of ATP8 and ATP6 Genes Rescues a MtDNA Complex V Null Mutant Nucleic Acids Research. Nov, 2016 | Pubmed ID: 27596602 Quantification of Lysine Acetylation and Succinylation Stoichiometry in Proteins Using Mass Spectrometric Data-Independent Acquisitions (SWATH) Journal of the American Society for Mass Spectrometry. Nov, 2016 | Pubmed ID: 27590315 Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4 The Journal of Biological Chemistry. 08, 2016 | Pubmed ID: 27358404 Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss Neuron. 04, 2016 | Pubmed ID: 27041503 Multiplexed, Scheduled, High-Resolution Parallel Reaction Monitoring on a Full Scan QqTOF Instrument with Integrated Data-Dependent and Targeted Mass Spectrometric Workflows Analytical Chemistry. Oct, 2015 | Pubmed ID: 26398777 Critical Role of Acetylation in Tau-mediated Neurodegeneration and Cognitive Deficits Nature Medicine. Oct, 2015 | Pubmed ID: 26390242 Protein Acetylation Dynamics in Response to Carbon Overflow in Escherichia Coli Molecular Microbiology. Dec, 2015 | Pubmed ID: 26264774 SIRT1 Deacetylates RORγt and Enhances Th17 Cell Generation The Journal of Experimental Medicine. May, 2015 | Pubmed ID: 25918343 Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma Molecular & Cellular Proteomics : MCP. Sep, 2015 | Pubmed ID: 25693799 Iron Promotes Protein Insolubility and Aging in C. Elegans Aging. Nov, 2014 | Pubmed ID: 25554795 Panorama: a Targeted Proteomics Knowledge Base Journal of Proteome Research. Sep, 2014 | Pubmed ID: 25102069 RPL24: a Potential Therapeutic Target Whose Depletion or Acetylation Inhibits Polysome Assembly and Cancer Cell Growth Oncotarget. Jul, 2014 | Pubmed ID: 24970821 Variation and Quantification Among a Target Set of Phosphopeptides in Human Plasma by Multiple Reaction Monitoring and SWATH-MS2 Data-independent Acquisition Electrophoresis. Dec, 2014 | Pubmed ID: 24853916 Structural, Kinetic and Proteomic Characterization of Acetyl Phosphate-dependent Bacterial Protein Acetylation PloS One. 2014 | Pubmed ID: 24756028 Phosphoprotein Secretome of Tumor Cells As a Source of Candidates for Breast Cancer Biomarkers in Plasma Molecular & Cellular Proteomics : MCP. Apr, 2014 | Pubmed ID: 24505115 Site-specific Acylation Changes in the Lipid A of Escherichia Coli LpxL Mutants Grown at High Temperatures Innate Immunity. Apr, 2014 | Pubmed ID: 23812252 Label-Free Quantitation and Mapping of the ErbB2 Tumor Receptor by Multiple Protease Digestion with Data-Dependent (MS1) and Data-Independent (MS2) Acquisitions International Journal of Proteomics. 2013 | Pubmed ID: 23710360 Label-free Quantitative Proteomics of the Lysine Acetylome in Mitochondria Identifies Substrates of SIRT3 in Metabolic Pathways Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23576753 Ligand Binding Promotes CDK-dependent Phosphorylation of ER-alpha on Hinge Serine 294 but Inhibits Ligand-independent Phosphorylation of Serine 305 Molecular Cancer Research : MCR. Aug, 2012 | Pubmed ID: 22669764 Ubiquitin-specific Peptidase 9, X-linked (USP9X) Modulates Activity of Mammalian Target of Rapamycin (mTOR) The Journal of Biological Chemistry. Jun, 2012 | Pubmed ID: 22544753 Platform-independent and Label-free Quantitation of Proteomic Data Using MS1 Extracted Ion Chromatograms in Skyline: Application to Protein Acetylation and Phosphorylation Molecular & Cellular Proteomics : MCP. May, 2012 | Pubmed ID: 22454539 Un Flusso Di Lavoro Scoperta Di Lectin Cromatografia Massa Spettrometria Identifica Putativi Biomarcatori Di Tumori Al Seno Aggressivo Journal of Proteome Research. Feb, 2012 | Pubmed ID: 22309216 Spettrometria Di Massa Identificazione Dei Siti Lisina Romanzo Acetilazione Dell'huntingtina Molecular & Cellular Proteomics : MCP. Oct, 2011 | Pubmed ID: 21685499 ScanRanker: Valutazione Della Qualità Di Spettri Di Massa Tandem Via Sequenza Tagging Journal of Proteome Research. Jul, 2011 | Pubmed ID: 21520941 Sicura Identificazione Dei 3-nitrotyrosine Modifiche Nei Dati Cristallografici Su Più Piattaforme Di Spettrometria Di Massa Journal of Proteomics. Oct, 2011 | Pubmed ID: 21514405 Un Workflow Di Affinità Lectina Targeting Strutture Glycosite Specifici, Legati Al Cancro Carboidrati Nel Plasma Umano Digerite Tripsina Analytical Biochemistry. Jan, 2011 | Pubmed ID: 20705048 Identificazione Di Nuovi Modulatori E Alterazioni Della Proteina in Non-apoptotic Morte Programmata Delle Cellule Journal of Cellular Biochemistry. Dec, 2010 | Pubmed ID: 20830744 Mirata Quantificazione Di Ossidazione Site Specific Cisteina in Proteine Endogene Utilizzando Un Differenziale Alchilazione E Monitoraggio Approccio Di Spettrometria Di Massa Multipla Di Reazione Molecular & Cellular Proteomics : MCP. Jul, 2010 | Pubmed ID: 20233844 Ripetibilità E Riproducibilità in Proteomic Identificazioni Di Spettrometria Di Massa Tandem Di Cromatografia Liquida Journal of Proteome Research. Feb, 2010 | Pubmed ID: 19921851 Studio Interlaboratorio Che Caratterizza Uno Standard Di Prestazioni Lievito Per L'analisi Comparativa Delle Prestazioni Di Piattaforma Di LC-MS Molecular & Cellular Proteomics : MCP. Feb, 2010 | Pubmed ID: 19858499 Misurazioni Delle Prestazioni Per Sistemi Liquid Chromatography-tandem Mass Spectrometry in Proteomics Analisi Molecular & Cellular Proteomics : MCP. Feb, 2010 | Pubmed ID: 19837981 Il Mycobacterium Bovis Bacillo Di Calmette-Guerin Fagosoma Proteome Molecular & Cellular Proteomics : MCP. Jan, 2010 | Pubmed ID: 19815536 Nitrazione Preferenzialmente Aumento Dell'alfa-sinucleina in Tirosina-39 in Un Modello Cellulare Ossidativo Del Morbo Di Parkinson Analytical Chemistry. Sep, 2009 | Pubmed ID: 19697948 Valutazione Multi-sito Della Precisione E La Riproducibilità Delle Misurazioni Multiple Con Reazione Basata Sul Monitoraggio Delle Proteine Nel Plasma Nature Biotechnology. Jul, 2009 | Pubmed ID: 19561596 IDPicker 2.0: Proteina Migliore Montaggio Con Alta Discriminazione Del Peptide Identificazione Filtraggio Journal of Proteome Research. Aug, 2009 | Pubmed ID: 19522537 Mappatura Sistematica Delle Modifiche Di Posttranslational in Umano Estrogeno Recettore Alfa Con Enfasi Sui Siti Di Fosforilazione Romanzo Molecular & Cellular Proteomics : MCP. Mar, 2009 | Pubmed ID: 18984578 Un Sito Di Fosforilazione Della Serina Romanzo Rilevato Nel Dominio N-terminale Del Recettore Estrogeno Isolato Da Cellule Di Cancro Al Seno Umano Journal of the American Society for Mass Spectrometry. May, 2008 | Pubmed ID: 18367407 Parziale Acetilazione Dei Residui Di Lisina Migliora Intraprotein Cross-linking Analytical Chemistry. Feb, 2008 | Pubmed ID: 18201069 Identificazione Di LpxL, Un Tardo Aciltransferasi Di Francisella Tularensis Infection and Immunity. Nov, 2007 | Pubmed ID: 17724076 Lo Stress Ossidativo Mitocondriale Provoca Iperfosforilazione Di Tau PloS One. 2007 | Pubmed ID: 17579710 Immunopurification Artigianale Di Citocromo C Ossidasi Per Un'analisi Di Multiplexing High-throughput Di Attività Enzimatica E Quantità Biotechnology and Applied Biochemistry. Dec, 2007 | Pubmed ID: 17508937 Caratterizzazione Di Lipidi Un Pattern Acilazione Francisella Tularensis, Francisella Novicida E Francisella Philomiragia Utilizzando Multi-fase Spettrometria Di Massa E Matrix-assisted Laser Desorbimento/ionizzazione Su Una Fonte Del Vuoto Intermedio Lineare Trappola Ionica Analytical Chemistry. Feb, 2007 | Pubmed ID: 17263332 Nuovi Percorsi Associati a Stress Chinone-indotta in Cellule Di Cancro Al Seno Drug Metabolism Reviews. 2006 | Pubmed ID: 17145690 Siti Di Fosforilazione Di Huntingtina Mappati Tramite Spettrometria Totale. Modulazione Di Scissione E Di Tossicità The Journal of Biological Chemistry. Aug, 2006 | Pubmed ID: 16782707 Analisi Proteomic Di Succinato Deidrogenasi E Ubichinolo-citocromo C Riduttasi (complesso II E III) Isolato Da Immunoprecipitazione Dai Mitocondri Di Cuore Di Bovino E Del Mouse Biochimica Et Biophysica Acta. Feb, 2006 | Pubmed ID: 16120479 Uno Studio Pilota Proteomic Interactiani Precursore Dell'amiloide Nella Malattia Di Alzheimer Annals of Neurology. Aug, 2005 | Pubmed ID: 16049941 Identificazione Spettrometria Di Massa Di Una Romanzo Fosforilazione Sito Nella Subunità NDUFA10 Del Complesso Mitocondriale Bovina FEBS Letters. Apr, 2005 | Pubmed ID: 15848193 Rapida Purificazione E Caratterizzazione Di Spettrometria Di Massa Di Deidrogenasi NADH Mitocondriale (complesso I) Dal Cervello Di Roditore E Una Linea Di Cellule Neuronali Dopaminergici Molecular & Cellular Proteomics : MCP. Jan, 2005 | Pubmed ID: 15591592 Romanzo Modificazione Dei Lipidi A Di Francisella Tularensis Infection and Immunity. Sep, 2004 | Pubmed ID: 15322031 Un Romanzo Lectina, DltA, è Necessaria Per L'espressione Di Un Fenotipo Di Resistenza Completa Siero in Haemophilus Ducreyi Infection and Immunity. Jun, 2004 | Pubmed ID: 15155648 Proteomic E Immunochimiche Caratterizzazione Di Un Ruolo Per Stathmin Nella Neurogenesi Adulta FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2004 | Pubmed ID: 14769823 Componenti Molecolari Di Un Percorso Di Morte Cellulare Attivati Da Stress Del Reticolo Endoplasmatico The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14561754 Isotopicamente Etichettati Reticolazione Reagenti: Risoluzione Di Degenerazione Di Massa Nell'identificazione Di Peptidi Di Reticolati Bioorganic & Medicinal Chemistry Letters. Nov, 2003 | Pubmed ID: 14592499 Phosphospecific Proteolisi Per Il Mapping Dei Siti Di Fosforilazione Della Proteina Nature Biotechnology. Sep, 2003 | Pubmed ID: 12923550 MS2Assign, Automatizzato Di Assegnazione E Nomenclatura Di Spettri Di Massa Tandem Di Chimicamente Reticolati Peptidi Journal of the American Society for Mass Spectrometry. Aug, 2003 | Pubmed ID: 12892908 Catepsina L in Vescicole Secretorie Funziona Come Un Proormone Elaborazione Enzima Per La Produzione Del Neurotrasmettitore Peptidico Encefalina Proceedings of the National Academy of Sciences of the United States of America. Aug, 2003 | Pubmed ID: 12869695 Metabolica Incorporazione Di Innaturali Sialico Acidi Haemophilus Ducreyi Lipooligosaccharides Proceedings of the National Academy of Sciences of the United States of America. Mar, 2003 | Pubmed ID: 12615992 Caratterizzazione Di Lipooligosaccharides Da Haemophilus Ducreyi Contenente Polylactosamine Si Ripete Journal of the American Society for Mass Spectrometry. Jun, 2002 | Pubmed ID: 12056572 Quantification of Insoluble Protein Aggregation in Caenorhabditis elegans during Aging with a Novel Data-Independent Acquisition Workflow JoVE 61366 생물학 Arricchimento simultaneo dell'affinità di due modifiche post-traduzionali per la quantificazione e la localizzazione del sito Xueshu Xie1, Samah Shah1, Anja Holtz1, Jacob Rose1, Nathan Basisty1, Birgit Schilling1 1Buck Institute for Research on Aging JoVE 60780 생물학 Quantificazione di site-specific Protein lisina acetilazione e stechiometria Succinylation usando la spettrometria totale di acquisizione dati-indipendente Lei Wei1, Jesse G. Meyer1, Birgit Schilling1 1Buck Institute for Research on Aging JoVE 57209 생물학 Un metodo HPLC lectina per arricchire Peptidi selettivamente glicosilata da campioni biologici complessi Eric Johansen1, Birgit Schilling2, Michael Lerch1, Richard K. Niles1, Haichuan Liu1, Bensheng Li2, Simon Allen1, Steven C. Hall1, H. Ewa Witkowska1, Fred E. Regnier3, Bradford W. Gibson2, Susan J. Fisher1, Penelope M. Drake1 1Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco - UCSF, 2Buck Institute for Age Research, 3Department of Chemistry, Purdue University JoVE 1398 생물학
Quantification of Insoluble Protein Aggregation in Caenorhabditis elegans during Aging with a Novel Data-Independent Acquisition Workflow JoVE 61366 생물학
Arricchimento simultaneo dell'affinità di due modifiche post-traduzionali per la quantificazione e la localizzazione del sito Xueshu Xie1, Samah Shah1, Anja Holtz1, Jacob Rose1, Nathan Basisty1, Birgit Schilling1 1Buck Institute for Research on Aging JoVE 60780 생물학
Quantificazione di site-specific Protein lisina acetilazione e stechiometria Succinylation usando la spettrometria totale di acquisizione dati-indipendente Lei Wei1, Jesse G. Meyer1, Birgit Schilling1 1Buck Institute for Research on Aging JoVE 57209 생물학
Un metodo HPLC lectina per arricchire Peptidi selettivamente glicosilata da campioni biologici complessi Eric Johansen1, Birgit Schilling2, Michael Lerch1, Richard K. Niles1, Haichuan Liu1, Bensheng Li2, Simon Allen1, Steven C. Hall1, H. Ewa Witkowska1, Fred E. Regnier3, Bradford W. Gibson2, Susan J. Fisher1, Penelope M. Drake1 1Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco - UCSF, 2Buck Institute for Age Research, 3Department of Chemistry, Purdue University JoVE 1398 생물학