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Immunology and Infection

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Un ensayo de microplacas para evaluar los efectos químicos sobre RBL-2H3 mástil degranulación: Efectos de Triclosan y sin uso de un disolvente orgánico

Article DOI: 10.3791/50671-v • 17:35 min • November 1st, 2013
November 1st, 2013 •
*1,2, *1,2, 1, 1,2
1Department of Molecular and Biomedical Sciences, University of Maine, Orono, 2Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono
* These authors contributed equally

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Degranulación de los mastocitos, la liberación de mediadores alérgicos, es importante en la alergia, el asma, y ​​la defensa parásito. Aquí demostramos técnicas 1 para evaluar los efectos de las drogas y las sustancias tóxicas en la degranulación, la metodología utilizada recientemente para exhibir el poderoso efecto inhibidor del agente antibacteriano triclosán 2.

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Inmunología Número 81 mastocitos basófilos degranulación RBL-2H3 triclosan irgasan antibacteriano β-hexosaminidasa alergia asma sustancias tóxicas ionóforo antígeno fluorescencia microplacas UV-Vis
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