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Static adhæsionsassayet for Studiet af Integrin Aktivering i T-lymfocytter

Article DOI: 10.3791/51646-v • 09:14 min • June 13th, 2014
June 13th, 2014 •
1, 1, 1, 1,2
1Department of Medicine, New York University School of Medicine, 2Departments of Pathology, New York University School of Medicine

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Statisk adhæsionsassay er et kraftfuldt værktøj, der kan bruges til at modellere interaktioner mellem T-lymfocytter og andre celletyper. Interaktioner genereres ved at injicere mærkede T-celler i brønde overtrukket med adhæsionsmolekyler, mens en pladelæser anvendes til at kvantificere antallet af adhærente celler efter seriel vask.

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Immunologi immunsystemet Phenomena T-celle vedhæftning RAP1 integriner T-lymfocytter ICAM-1
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