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Journal / Developmental Biology / Driedimensionale Kwantificering van Dendritische…
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Developmental Biology

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JoVE Journal Developmental Biology
Driedimensionale Kwantificering van Dendritische stekels van Piramidale Neuronen afgeleid van menselijk geïnduceerde pluripotente stamcellen
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Driedimensionale Kwantificering van Dendritische stekels van Piramidale Neuronen afgeleid van menselijk geïnduceerde pluripotente stamcellen

Article DOI: 10.3791/53197-v • 10:18 min • October 10th, 2015
October 10th, 2015 •
1,2,3, 4, 1,2,3, 5, 1,2,3, 1,2,3
1Human Genetics and Cognitive Functions, Institut Pasteur, 2CNRS URA 2182 'Genes, synapses and cognition', Institut Pasteur, 3Human Genetics and Cognitive Functions, Université Paris Diderot, Sorbonne Paris Cité, 4Plateforme d' Imagerie Dynamique, Imagopole, CiTech, Institut Pasteur, 5Neuroplasticity and Therapeutics, CECS, I-STEM, AFM, Evry

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Dendritische stekels van piramidale neuronen zijn de sites van de meest prikkelende synapsen in de hersenen van zoogdieren cortex. Deze methode beschrijft een 3D-kwantitatieve analyse van de wervelkolom morfologie in menselijke corticale piramidale glutamaat neuronen afgeleid van geïnduceerde pluripotente stamcellen.

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Developmental Biology Human iPSC-afgeleide neuronen piramidale neuronen dendritische wervelkolom rijping wervelkolom beeldvorming 3D-kwantificering confocale microscopie
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