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Enfoque preciso de la ablación celular para modelar lesiones renales agudas en el desarrollo de pez cebra

Article DOI: 10.3791/55606-v • 09:53 min • June 3rd, 2017
June 3rd, 2017 •
1, 1, 2, 1, 1, 1
1Department of Biomedical Sciences, NYITCOM, 2Department of Basic Sciences, NYITCOM-A-State

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Este trabajo presenta un nuevo modelo in vivo de lesión renal segmentaria utilizando el pez cebra transgénico GFP de riñón. El modelo permite la inducción de la ablación específica de las células epiteliales del riñón para mostrar los mecanismos celulares de la lesión nefrona y la reparación.

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Biología del desarrollo Número 124 Riñón pez cebra GFP células epiteliales láser fotoablación confocal
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