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JoVE Journal
Genetics

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Canalostomy als een chirurgische benadering van lokale Drug Delivery tot de Inner oren van volwassen en neonatale muizen

Article DOI: 10.3791/57351-v • 09:34 min • May 25th, 2018
May 25th, 2018 •
1, 1, 1, 2, 1, 1, 1
1Department of Otolaryngology-Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, 2Department of Otolaryngology-Head and Neck Surgery, Shanghai First People's Hospital, Shanghai Jiao Tong University

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Hier beschrijven we canalostomy procedure waarmee lokale drug levering tot de inner oren van volwassen en neonatale muizen door het semicircular kanaal met minimale schade aan gehoorbescherming en vestibulaire functie. Deze methode kan worden gebruikt om te enten virale vectoren, farmaceutische producten en kleine moleculen in het binnenoor muis.

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Deze maand in JoVE kwestie 135 Canalostomy slak vestibule haarcel lokale drug delivery semicircular kanaal neonatale
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