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Immunology and Infection

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Riktad antikropp blockering av en dual-funktionell konjugat av antigen peptid och FC-III mimetika (DCAF)
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Riktad antikropp blockering av en dual-funktionell konjugat av antigen peptid och FC-III mimetika (DCAF)

Article DOI: 10.3791/60063-v • 09:39 min • September 17th, 2019
September 17th, 2019 •
*1,2, *3, 2, 2, 2, 3, 1,2
1Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, 2Mass Spectrometry Core Facility, School of Life Sciences, Westlake University, 3MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University
* These authors contributed equally

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Utveckling av en dual-funktionell konjugat av antigen peptid och FC-III mimetika (DCAF) är nytt för eliminering av skadliga antikroppar. Här beskriver vi ett detaljerat protokoll för syntes av DCAF1 molekyl, som selektivt kan blockera 4G2 antikropp för att eliminera antikroppsberoende förbättring effekt under Dengue virusinfektion.

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Retraktion DCAF riktad terapi antikropp ursprunglig kemisk ligering solid fas peptid syntes proteinuttryck och rening ELISA
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