Waiting
Processando Login

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Performing Subretinal Injections in Rodents to…
JoVE Journal
Medicine

É necessário ter uma assinatura JoVE para assistir este

JoVE Journal Medicine
Performing Subretinal Injections in Rodents to Deliver Retinal Pigment Epithelium Cells in Suspension
Dorsal Column Steerability with Dual Parallel Leads using Dedicated Power Sources: A Computational Model
Journal (Medicine)
Dorsal Column Steerability with Dual Parallel Leads using Dedicated Power Sources: A Computational Model
Cavernous Nerve Stimulation and Recording of Intracavernous Pressure in a Rat
Journal (Medicine)
Cavernous Nerve Stimulation and Recording of Intracavernous Pressure in a Rat
 

Performing Subretinal Injections in Rodents to Deliver Retinal Pigment Epithelium Cells in Suspension

Article DOI: 10.3791/52247-v • 06:04 min • January 23rd, 2015
January 23rd, 2015 •
1,2, 1, 1, 1, 2, 1, 1,2
1Department of Cell and Molecular Biology, The Scripps Research Institute, 2Lowy Medical Research Institute

Capítulos

Resumo
Automatic Translation

Here we present a community accepted protocol in multimedia format for subretinally injecting a bolus of RPE cells in rats and mice. This approach can be used for determining rescue potentials, safety profiles, and survival capacities of grafted RPE cells upon implantation in animal models of retinal degeneration.

Tags

Subretinal Injections Rodents Retinal Pigment Epithelium Cells Suspension Light To Electrical Impulses Rod And Cone Photoreceptors Age-related Macular Degeneration AMD Permanent Vision Loss Implantation Of Healthy RPE Cells Pluripotent Stem Cells Safety And Efficacy Animal Models Injecting RPE Cells Creating A Hole In The Eye Sharp Needle Syringe With Blunt Needle Vitreous Integration Of Stem Cell-derived RPE Cells Photoreceptor Degeneration
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter