38,181 Views
•
12:47 min
•
February 03, 2012
DOI:
Summary
Automatically generated
Spectral Karyotyping (SKY) is an advanced cytogenetics technique to identify genomic and chromosomal aberrations. This technique takes advantage of chromosome painting probes, which allow classification of all chromosomes. SKY can also identify complex chromosome aberrations and segregation defects in mice and humans with various diseases, including polycystic kidney disease.
Explore More Videos
Related Videos
09:06
Orthotopic Aortic Transplantation in Mice for the Study of Vascular Disease
Related Videos
10773 Views
08:50
5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Related Videos
23397 Views
08:50
Assessment of Vascular Function in Patients With Chronic Kidney Disease
Related Videos
16113 Views
10:51
A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys
Related Videos
11026 Views
07:35
Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Related Videos
11404 Views
08:29
Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
Related Videos
13861 Views
09:54
A Model to Simulate Clinically Relevant Hypoxia in Humans
Related Videos
8707 Views
06:19
In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy
Related Videos
10474 Views
09:16
Assessment of Kidney Function in Mouse Models of Glomerular Disease
Related Videos
17277 Views
07:01
Delivery of Exogenous Artificially Synthesized miRNA Mimic to the Kidney Using Polyethylenimine Nanoparticles in Several Kidney Disease Mouse Models
Related Videos
1468 Views
Read Article
Cite this Article
AbouAlaiwi, W. A., Rodriguez, I., Nauli, S. M. Spectral Karyotyping to Study Chromosome Abnormalities in Humans and Mice with Polycystic Kidney Disease. J. Vis. Exp. (60), e3887, doi:10.3791/3887 (2012).
Copy