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Chapters
- 00:05Title
- 01:20Sample Slide Preparation
- 01:54Localization of Metaphases Using an Automated System
- 02:25Hybridization
- 04:26Chromosomics
- 05:29Conclusion
A novel fluorescence in situ hybridization (FISH) method that simultaneously examines both numerical and structural chromosome alterations, particularly the specific chromosomal translocations associated with leukemia and lymphoma, of all 24 human chromosomes on a single device in one hybridization, is described.
Tags
ChromosomicsNumerical AlterationsStructural AlterationsHuman ChromosomesOctoChrome FISH AssayFluorescence In Situ HybridizationDNA ProbesCytogeneticsChromosome AberrationsBenzene ExposureBenzene-poisoning PatientsHealthy WorkersLeukemia-specific Chromosomal AlterationsCytogentic ChangesBenzene-induced LeukemogenesisSingle FISH AssayWhole ChromosomesSpecific LociMultiple SlidesSpectral KaryotypingWhole Genome Visualization
