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JoVE Journal
Immunology and Infection

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Bioluminescence Imaging of NADPH Oxidase Activity in Different Animal Models
 

Bioluminescence Imaging of NADPH Oxidase Activity in Different Animal Models

Article DOI: 10.3791/3925
October 22nd, 2012

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Summary October 22nd, 2012

NADPH oxidase is the major source of reactive oxygen species (ROS) in phagocytes. Because of the ephemeral nature of ROS, it is difficult to measure and monitor ROS levels in living animals. A minimally invasive method for serial quantification of ROS in living mice is described.

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