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Cell Co-culture Patterning Using Aqueous Two-phase Systems

Article DOI: 10.3791/50304 • 10:11 min
March 26th, 2013 •
1, 1, 1, 1,2
1Department of Biomedical Engineering, University of Michigan, 2Department of Macromolecular Science and Engineering, University of Michigan

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March 26th, 2013

Aqueous two-phase systems were used to simultaneously pattern multiple populations of cells. This fast and easy method for cell patterning takes advantage of the phase separation of aqueous solutions of dextran and polyethylene glycol and the interfacial tension that exists between the two polymer solutions.

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