Biology
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Bottom-up and Shotgun Proteomics to Identify a Comprehensive Cochlear Proteome
Chapters
Summary March 7th, 2014
Proteome analysis of the cochlear sensory epithelium can be challenging due to its small size and because membrane proteins are difficult to isolate and identify. Both membrane and soluble proteins can be identified by combining multiple preparative methods and separation techniques along with high-resolution mass spectrometry.
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