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JoVE Journal Medicine
Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion
 

Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion

Article doi: 10.3791/60195
September 25th, 2019 •
1, 2, 1, 1
1Department of Biological Sciences, Carnegie Mellon University, 2QPathology

Summary
Automatic Translation
September 25th, 2019

Nanoscale imaging of clinical tissue samples can improve understanding of disease pathogenesis. Expansion pathology (ExPath) is a version of expansion microscopy (ExM), modified for compatibility with standard clinical tissue samples, to explore the nanoscale configuration of biomolecules using conventional diffraction limited microscopes.

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