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Biology

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Development of a Cell Co-Culture Model to Mimic Cardiac Ischemia/Reperfusion In Vitro
 

Development of a Cell Co-Culture Model to Mimic Cardiac Ischemia/Reperfusion In Vitro

Article DOI: 10.3791/62913-v
October 13th, 2021

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Summary October 13th, 2021

Spatial distance is a key parameter in assessing hypoxia/reoxygenation injury in a co-culture model of separate endothelial and cardiomyocyte cell layers, suggesting, for the first time, that optimizing the co-culture spatial environment is necessary to provide a favorable in vitro model for testing the role of endothelial cells in cardiomyocyte protection.

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