Peltier Thermodes
Peltier Thermodes - Related Videos
06:31
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Cited by 2 •
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We present a protocol to study the formation of hydrates in the presence of nonionic surfactants on the interface of a water droplet submerged in cyclopentane. The protocol consists of building a low-cost, programmable, temperature regulator. The temperature control system is combined with visualization techniques and internal pressure measurements.
09:10
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07:47
Surgical Ablation Assay for Studying Eye Regeneration in Planarians
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Cited by 3 •
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10:47
Whole-body Mass Spectrometry Imaging by Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI)
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Cited by 19 •
2016
A mass spectrometry imaging (MSI) source operated at atmospheric pressure was developed by coupling mid-infrared laser desorption and electrospray post-ionization. Exogenous ice matrix was used as the energy-absorbing matrix to facilitate resonant desorption of tissue-related material. This manuscript provides a step-by-step protocol for performing IR-MALDESI MSI of whole-body neonatal mouse.
09:09
Design and Analysis of Temperature Preference Behavior and its Circadian Rhythm in Drosophila
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Cited by 26 •
2014
We recently identified a novel Drosophila circadian output, temperature preference rhythm (TPR), in which the preferred temperature in flies rises during the day and falls during the night. TPR is regulated independently from another circadian output, locomotor activity. Here we describe the design and analysis of TPR in Drosophila.
FAQs
The electric current crosses a junction between dissimilar semiconductor materials and transfers heat across that junction. Changing the current direction changes which side receives heat and which side loses it. This reversible behavior lets an experimenter switch between heating and cooling without changing the contact device, supporting controlled thermal stimulation during an experiment.
Rapid switching allows temperature changes to occur on a carefully controlled experimental timescale. That timing helps researchers relate a specific thermal event to a sensory response or subsequent behavior. It also supports experiments involving changing stimuli, where the sequence and timing of temperature conditions must remain consistent across repeated trials.
Programmable temperatures let researchers specify the thermal conditions delivered by the contact surface rather than relying on uncontrolled environmental changes. Repeatable stimulation makes responses easier to compare across trials and participants. Together, these features support systematic studies of how different temperature conditions influence sensation, pain perception, learning, or behavioral responses.
A thermode is placed against the skin to provide a controlled thermal stimulus while the experiment records the resulting behavior or reported sensation. The researcher can vary the temperature and timing according to the experimental design, then compare responses under different conditions. This arrangement connects a defined sensory input with an observable behavioral outcome.
Controlled thermal stimulation can be used to examine temperature sensation and pain perception, as well as learning and responses to changing environmental conditions. Because the stimulus can be delivered in a controlled and repeatable way, researchers can compare behavioral responses across programmed temperature conditions instead of treating temperature as an incidental feature of the environment.
Their fast switching, programmable temperatures, and repeatable stimulation provide a defined sensory input that can be aligned with behavioral measurements. In behavioral research, this makes it possible to examine how an organism responds when the thermal condition changes at a planned point in the experiment. The approach therefore supports precise comparisons between stimulus conditions and behavioral outcomes.