Alain Destée Team "Early Stages of Parkinson's Disease" of the Jean-Pierre Aubert Research Center INSERM UMR-S1172, CHRU Lille, University of Lille 1 and Lille 2 Biography Publications Institution JoVE Articles Alain Destée has not added a biography. If you are Alain Destée and would like to personalize this page please email our Author Liaison for assistance. Publications Falls in Ambulatory Non-demented Patients with Parkinson's Disease Journal of Neural Transmission (Vienna, Austria : 1996). Apr, 2015 | Pubmed ID: 25845678 Polymorphism of the Dopamine Transporter Type 1 Gene Modifies the Treatment Response in Parkinson's Disease Brain : a Journal of Neurology. May, 2015 | Pubmed ID: 25805645 TMEM240 Mutations Cause Spinocerebellar Ataxia 21 with Mental Retardation and Severe Cognitive Impairment Brain : a Journal of Neurology. Oct, 2014 | Pubmed ID: 25070513 Prevalence, Determinants, and Effect on Quality of Life of Freezing of Gait in Parkinson Disease JAMA Neurology. Jul, 2014 | Pubmed ID: 24839938 Predictive Factors for Improvement of Gait by Low-frequency Stimulation in Parkinson's Disease Journal of Parkinson's Disease. 2014 | Pubmed ID: 24763085 Attention Modulates Step Initiation Postural Adjustments in Parkinson Freezers Parkinsonism & Related Disorders. Mar, 2014 | Pubmed ID: 24405757 Withdrawing Amantadine in Dyskinetic Patients with Parkinson Disease: the AMANDYSK Trial Neurology. Jan, 2014 | Pubmed ID: 24371304 Involvement of the Immune System, Endocytosis and EIF2 Signaling in Both Genetically Determined and Sporadic Forms of Parkinson's Disease Neurobiology of Disease. Mar, 2014 | Pubmed ID: 24269915 Targeting Chelatable Iron As a Therapeutic Modality in Parkinson's Disease Antioxidants & Redox Signaling. Jul, 2014 | Pubmed ID: 24251381 Rivastigmine in Apathetic but Dementia and Depression-free Patients with Parkinson's Disease: a Double-blind, Placebo-controlled, Randomised Clinical Trial Journal of Neurology, Neurosurgery, and Psychiatry. Jun, 2014 | Pubmed ID: 24218528 Protective Effect of LRRK2 P.R1398H on Risk of Parkinson's Disease is Independent of MAPT and SNCA Variants Neurobiology of Aging. Jan, 2014 | Pubmed ID: 23962496 Multiclass Classification of FDG PET Scans for the Distinction Between Parkinson's Disease and Atypical Parkinsonian Syndromes NeuroImage. Clinical. 2013 | Pubmed ID: 24179839 AFQ056 in Parkinson Patients with Levodopa-induced Dyskinesia: 13-week, Randomized, Dose-finding Study Movement Disorders : Official Journal of the Movement Disorder Society. Nov, 2013 | Pubmed ID: 23853029 Association Between Caffeine Intake and Age at Onset in Huntington's Disease Neurobiology of Disease. Oct, 2013 | Pubmed ID: 23732677 Memantine for Axial Signs in Parkinson's Disease: a Randomised, Double-blind, Placebo-controlled Pilot Study Journal of Neurology, Neurosurgery, and Psychiatry. May, 2013 | Pubmed ID: 23077087 Spastic Paraplegia Gene 7 in Patients with Spasticity And/or Optic Neuropathy Brain : a Journal of Neurology. Oct, 2012 | Pubmed ID: 23065789 Effect of Intermittent Theta-burst Stimulation on Akinesia and Sensorimotor Integration in Patients with Parkinson's Disease The European Journal of Neuroscience. Sep, 2012 | Pubmed ID: 22693966 Methylphenidate for Gait Hypokinesia and Freezing in Patients with Parkinson's Disease Undergoing Subthalamic Stimulation: a Multicentre, Parallel, Randomised, Placebo-controlled Trial The Lancet. Neurology. Jul, 2012 | Pubmed ID: 22658702 Role of Basal Ganglia Circuits in Resisting Interference by Distracters: a SwLORETA Study PloS One. 2012 | Pubmed ID: 22470542 Modifying Effect of Arterial Hypertension on Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. Feb, 2012 | Pubmed ID: 21913867 Spinocerebellar Ataxia: a Rational Approach to Aetiological Diagnosis Cerebellum (London, England). Mar, 2012 | Pubmed ID: 21892625 Translation Initiator EIF4G1 Mutations in Familial Parkinson Disease American Journal of Human Genetics. Sep, 2011 | Pubmed ID: 21907011 Role of Sepiapterin Reductase Gene at the PARK3 Locus in Parkinson's Disease Neurobiology of Aging. Nov, 2011 | Pubmed ID: 21782285 Are Gait Initiation Parameters Early Markers of Huntington's Disease in Pre-manifest Mutation Carriers? Gait & Posture. Jun, 2011 | Pubmed ID: 21616667 Singular DYT6 Phenotypes in Association with New THAP1 Frameshift Mutations Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2011 | Pubmed ID: 21520283 Modulation of Dysarthropneumophonia by Low-frequency STN DBS in Advanced Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2011 | Pubmed ID: 21506146 SNCA Locus Duplication Carriers: from Genetics to Parkinson Disease Phenotypes Human Mutation. Apr, 2011 | Pubmed ID: 21412942 Independent and Joint Effects of the MAPT and SNCA Genes in Parkinson Disease Annals of Neurology. May, 2011 | Pubmed ID: 21391235 External Globus Pallidus Stimulation Modulates Brain Connectivity in Huntington's Disease Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2011 | Pubmed ID: 20959850 Transcriptional Profile of Parkinson Blood Mononuclear Cells with LRRK2 Mutation Neurobiology of Aging. Oct, 2011 | Pubmed ID: 20096956 Memantine for Patients with Parkinson's Disease Dementia or Dementia with Lewy Bodies: a Randomised, Double-blind, Placebo-controlled Trial The Lancet. Neurology. Oct, 2010 | Pubmed ID: 20729148 Differing Short-term Neuroprotective Effects of the Fibrates Fenofibrate and Bezafibrate in MPTP and 6-OHDA Experimental Models of Parkinson's Disease Behavioural Pharmacology. May, 2010 | Pubmed ID: 20440202 Cognitive Complaints in Parkinson's Disease: Its Relationship with Objective Cognitive Decline Journal of Neurology. Jan, 2010 | Pubmed ID: 19690907 Apathy May Herald Cognitive Decline and Dementia in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2009 | Pubmed ID: 19908317 STN Versus PPN-DBS for Alleviating Freezing of Gait: Toward a Frequency Modulation Approach? Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2009 | Pubmed ID: 19705483 Bilateral Pallidal Deep Brain Stimulation for the Treatment of Patients with Dystonia-choreoathetosis Cerebral Palsy: a Prospective Pilot Study The Lancet. Neurology. Aug, 2009 | Pubmed ID: 19576854 Lipid-lowering Drugs Are Associated with Delayed Onset and Slower Course of Parkinson's Disease Pharmacological Research. Jul, 2009 | Pubmed ID: 19427584 Levodopa for Parkinson's Disease The New England Journal of Medicine. Feb, 2009 | Pubmed ID: 19246370 Motor-related Circuit Dysfunction in MSA-P: Usefulness of Combined Whole-brain Imaging Analysis Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2009 | Pubmed ID: 19194988 CSF Profiles of Angiogenic and Inflammatory Factors Depend on the Respiratory Status of ALS Patients Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. Jun, 2009 | Pubmed ID: 19177252 A New Perspective on Brain Derived Neurotrophin Factor Polymorphism in L-dopa Induced Dyskinesia Journal of Neurology, Neurosurgery, and Psychiatry. Feb, 2009 | Pubmed ID: 19151015 Alpha-synuclein Gene Rearrangements in Dominantly Inherited Parkinsonism: Frequency, Phenotype, and Mechanisms Archives of Neurology. Jan, 2009 | Pubmed ID: 19139307 Myoclonus of Peripheral Origin: Two Case Reports Movement Disorders : Official Journal of the Movement Disorder Society. Jan, 2009 | Pubmed ID: 19086086 Is There a Difference Between Levodopa/ Dopa-decarboxylase Inhibitor and Entacapone and Levodopa/dopa-decarboxylase Inhibitor Dose Fractionation Strategies in Parkinson's Disease Patients Experiencing Symptom Re-emergence Due to Wearing-off? The Honeymoon Study European Neurology. 2009 | Pubmed ID: 19039224 Clinical Features and Natural History of Neuroferritinopathy Caused by the 458dupA FTL Mutation Brain : a Journal of Neurology. Jun, 2009 | Pubmed ID: 18854324 Early Dopasensitive Parkinsonism Related to Myotonic Dystrophy Type 2 Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2008 | Pubmed ID: 18759330 Attenuated Presentation of Ataxia-telangiectasia with Familial Cancer History Journal of Neurology. Aug, 2008 | Pubmed ID: 18575927 Effect of External Cueing on Gait in Huntington's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Jul, 2008 | Pubmed ID: 18512747 Comparison of Desipramine and Citalopram Treatments for Depression in Parkinson's Disease: a Double-blind, Randomized, Placebo-controlled Study Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2008 | Pubmed ID: 18311826 The Lille Apathy Rating Scale: Validation of a Caregiver-based Version Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2008 | Pubmed ID: 18307266 Effect of Dopaminergic Substances on Sleep/wakefulness in Saline- and MPTP-treated Mice Journal of Sleep Research. Mar, 2008 | Pubmed ID: 18275560 MPTP-treated Mice: Long-lasting Loss of Nigral TH-ir Neurons but Not Paradoxical Sleep Alterations Experimental Brain Research. Apr, 2008 | Pubmed ID: 18224307 Role of Attentional Resources on Gait Performance in Huntington's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2008 | Pubmed ID: 18175353 Acute Deep-brain Stimulation of the Internal and External Globus Pallidus in Primary Dystonia: Functional Mapping of the Pallidum Archives of Neurology. Sep, 2007 | Pubmed ID: 17846266 Exhaustive, One-year Follow-up of Subthalamic Nucleus Deep Brain Stimulation in a Large, Single-center Cohort of Parkinsonian Patients Neurosurgery. Aug, 2007 | Pubmed ID: 17762742 Is the Paced Auditory Serial Addition Test (PASAT) a Valid Means of Assessing Executive Function in Parkinson's Disease? Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. Jul, 2007 | Pubmed ID: 17715795 Effects of Pulse Width Variations in Pallidal Stimulation for Primary Generalized Dystonia Journal of Neurology. Nov, 2007 | Pubmed ID: 17597333 The Effects of Serotoninergic, Noradrenergic, Cholinergic and Dopaminergic Drugs on Vigilance States in MPTP-treated Mice Brain Research. Aug, 2007 | Pubmed ID: 17586479 Neurodegeneration with Brain Iron Accumulation: Clinical, Radiographic and Genetic Heterogeneity and Corresponding Therapeutic Options Acta Neurologica Belgica. Mar, 2007 | Pubmed ID: 17569231 Oral Festination in Parkinson's Disease: Biomechanical Analysis and Correlation with Festination and Freezing of Gait Movement Disorders : Official Journal of the Movement Disorder Society. Jul, 2007 | Pubmed ID: 17516477 LRRK2 Exon 41 Mutations in Sporadic Parkinson Disease in Europeans Archives of Neurology. Mar, 2007 | Pubmed ID: 17353388 Bilateral, Pallidal, Deep-brain Stimulation in Primary Generalised Dystonia: a Prospective 3 Year Follow-up Study The Lancet. Neurology. Mar, 2007 | Pubmed ID: 17303528 Characteristics of Apathy in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Apr, 2007 | Pubmed ID: 17290451 Lipid-lowering Drugs in the MPTP Mouse Model of Parkinson's Disease: Fenofibrate Has a Neuroprotective Effect, Whereas Bezafibrate and HMG-CoA Reductase Inhibitors Do Not Brain Research. Mar, 2007 | Pubmed ID: 17196944 New Syndromic Form of Benign Hereditary Chorea is Associated with a Deletion of TITF-1 and PAX-9 Contiguous Genes Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2006 | Pubmed ID: 17044090 Utility of the Mattis Dementia Rating Scale to Assess the Efficacy of Rivastigmine in Dementia Associated with Parkinson's Disease Journal of Neurology. Sep, 2006 | Pubmed ID: 16998649 Role of Hypokinesia and Bradykinesia in Gait Disturbances in Huntington's Disease: a Biomechanical Study Journal of Neurology. Jan, 2006 | Pubmed ID: 16096818 Corticobasal Degeneration and Parkinson's Disease Assessed by HmPaO SPECT: the Utility of Factorial Discriminant Analysis Movement Disorders : Official Journal of the Movement Disorder Society. Nov, 2005 | Pubmed ID: 16007659 [Therapeutic Strategies for Parkinson's Disease] La Revue Du Praticien. Apr, 2005 | Pubmed ID: 15966415 Abnormal Cortical Mechanisms in Voluntary Muscle Relaxation in De Novo Parkinsonian Patients Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. Jun, 2005 | Pubmed ID: 15933492 Ictal Movement Disorders and Hypothalamic Hamartoma Epileptic Disorders : International Epilepsy Journal with Videotape. Mar, 2005 | Pubmed ID: 15741140 Clinical and Genetic Evaluation in a French Population Presenting with Primary Focal Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Jul, 2005 | Pubmed ID: 15726581 Bilateral Deep-brain Stimulation of the Globus Pallidus in Primary Generalized Dystonia The New England Journal of Medicine. Feb, 2005 | Pubmed ID: 15689584 Cognitive and SPECT Characteristics Predict Progression of Parkinson's Disease in Newly Diagnosed Patients Journal of Neurology. Nov, 2004 | Pubmed ID: 15592735 Orofacial Apraxia in Corticobasal Degeneration, Progressive Supranuclear Palsy, Multiple System Atrophy and Parkinson's Disease Journal of Neurology. Nov, 2004 | Pubmed ID: 15592726 Vigilance States in a Parkinsonian Model, the MPTP Mouse The European Journal of Neuroscience. Nov, 2004 | Pubmed ID: 15525288 Alpha-synuclein Locus Duplication As a Cause of Familial Parkinson's Disease Lancet. Sep 25-Oct 1, 2004 | Pubmed ID: 15451224 Comparison of Secondary Vascular Prevention in Practice After Cerebral Ischemia and Coronary Heart Disease Journal of Neurology. May, 2004 | Pubmed ID: 15164184 Effects of Subthalamic Nucleus Stimulation on Parkinsonian Dysarthria and Speech Intelligibility Journal of Neurology. Mar, 2004 | Pubmed ID: 15015014 Deficits in Decoding Emotional Facial Expressions in Parkinson's Disease Neuropsychologia. 2004 | Pubmed ID: 14644109 Retinal Involvement in Dementia with Lewy Bodies: a Clue to Hallucinations? Annals of Neurology. Oct, 2003 | Pubmed ID: 14520672 How Much Phenotypic Variation Can Be Attributed to Parkin Genotype? Annals of Neurology. Aug, 2003 | Pubmed ID: 12891670 Executive Function Differences in Multiple System Atrophy and Parkinson's Disease Parkinsonism & Related Disorders. Mar, 2003 | Pubmed ID: 12618055 Effects of Subthalamic Nucleus Stimulation and Levodopa Treatment on Gait Abnormalities in Parkinson Disease Archives of Neurology. Jan, 2003 | Pubmed ID: 12533092 Relationship Between Oscillations in the Basal Ganglia and Synchronization of Cortical Activity Epileptic Disorders : International Epilepsy Journal with Videotape. Dec, 2002 | Pubmed ID: 12495873 A New Locus for Spinocerebellar Ataxia (SCA21) Maps to Chromosome 7p21.3-p15.1 Annals of Neurology. Nov, 2002 | Pubmed ID: 12402269 Mutation Analysis and Association Studies of the Ubiquitin Carboxy-terminal Hydrolase L1 Gene in Huntington's Disease Neuroscience Letters. Aug, 2002 | Pubmed ID: 12123845 Influence of Pallidal Stimulation and Levodopa on Gait and Preparatory Postural Adjustments in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Jan, 2002 | Pubmed ID: 11835442 Xenopus laevis as a Model to Identify Translation Impairment Amélie de Broucker1, Pierre Semaille1, Katia Cailliau2, Alain Martoriati2, Thomas Comptdaer1, Jean-François Bodart2, Alain Destée1, Marie-Christine Chartier-Harlin1 1Team "Early Stages of Parkinson's Disease" of the Jean-Pierre Aubert Research Center, INSERM UMR-S1172, CHRU Lille, University of Lille 1 and Lille 2, 2Team "Signal Division Regulation", CNRS UMR 8576, University of Lille 1 JoVE 52724 Biology
Xenopus laevis as a Model to Identify Translation Impairment Amélie de Broucker1, Pierre Semaille1, Katia Cailliau2, Alain Martoriati2, Thomas Comptdaer1, Jean-François Bodart2, Alain Destée1, Marie-Christine Chartier-Harlin1 1Team "Early Stages of Parkinson's Disease" of the Jean-Pierre Aubert Research Center, INSERM UMR-S1172, CHRU Lille, University of Lille 1 and Lille 2, 2Team "Signal Division Regulation", CNRS UMR 8576, University of Lille 1 JoVE 52724 Biology