Alexander Thielen Biography Publications JoVE Articles Alexander Thielen has not added a biography. If you are Alexander Thielen and would like to personalize this page please email our Author Liaison for assistance. Publications Geno2pheno[454]: A Web Server for the Prediction of HIV-1 Coreceptor Usage from Next-Generation Sequencing Data Intervirology. 2012 | Pubmed ID: 22286879 HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge Intervirology. 2012 | Pubmed ID: 22286877 APOBEC3G/F As One Possible Driving Force for Co-receptor Switch of the Human Immunodeficiency Virus-1 Medical Microbiology and Immunology. Feb, 2012 | Pubmed ID: 21573951 Deep V3 Sequencing for HIV Type 1 Tropism in Treatment-naive Patients: a Reanalysis of the MERIT Trial of Maraviroc Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Oct, 2011 | Pubmed ID: 21890778 HIV-1 Mutational Pathways Under Multidrug Therapy AIDS Research and Therapy. 2011 | Pubmed ID: 21794106 High Concordance Between the Position-specific Scoring Matrix and Geno2pheno Algorithms for Genotypic Interpretation of HIV-1 Tropism: V3 Length As the Major Cause of Disagreement Journal of Clinical Microbiology. Sep, 2011 | Pubmed ID: 21734029 Added Value of Deep Sequencing Relative to Population Sequencing in Heavily Pre-treated HIV-1-infected Subjects PloS One. 2011 | Pubmed ID: 21602929 Genotypic Tropism Testing by Massively Parallel Sequencing: Qualitative and Quantitative Analysis BMC Medical Informatics and Decision Making. 2011 | Pubmed ID: 21569501 Mutations in Gp41 Are Correlated with Coreceptor Tropism but Do Not Improve Prediction Methods Substantially Antiviral Therapy. 2011 | Pubmed ID: 21555814 Deep Sequencing to Infer HIV-1 Co-receptor Usage: Application to Three Clinical Trials of Maraviroc in Treatment-experienced Patients The Journal of Infectious Diseases. Jan, 2011 | Pubmed ID: 21288824 In-depth Analysis of G-to-A Hypermutation Rate in HIV-1 Env DNA Induced by Endogenous APOBEC3 Proteins Using Massively Parallel Sequencing Journal of Virological Methods. Feb, 2011 | Pubmed ID: 21111003 Dynamic Escape of Pre-existing Raltegravir-resistant HIV-1 from Raltegravir Selection Pressure Antiviral Research. Dec, 2010 | Pubmed ID: 20883724 Improved Prediction of HIVâ€1 Coreceptor Usage with Sequence Information from the Second Hypervariable Loop of Gp120 The Journal of Infectious Diseases. Nov, 2010 | Pubmed ID: 20874088 Population-based V3 Genotypic Tropism Assay: a Retrospective Analysis Using Screening Samples from the A4001029 and MOTIVATE Studies AIDS (London, England). Oct, 2010 | Pubmed ID: 20736814 Improved Detection of CXCR4-using HIV by V3 Genotyping: Application of Population-based and "deep" Sequencing to Plasma RNA and Proviral DNA Journal of Acquired Immune Deficiency Syndromes (1999). Aug, 2010 | Pubmed ID: 20512044 Decreased HIV Diversity After Allogeneic Stem Cell Transplantation of an HIV-1 Infected Patient: a Case Report Virology Journal. 2010 | Pubmed ID: 20210988 V3 Loop Sequence Space Analysis Suggests Different Evolutionary Patterns of CCR5- and CXCR4-tropic HIV PloS One. 2009 | Pubmed ID: 19816596 Bioinformatics Prediction of HIV Coreceptor Usage Nature Biotechnology. Dec, 2007 | Pubmed ID: 18066037 Prediction of HIV-1 Coreceptor Usage (Tropism) by Sequence Analysis using a Genotypic Approach JoVE 3264 Immunology and Infection
Prediction of HIV-1 Coreceptor Usage (Tropism) by Sequence Analysis using a Genotypic Approach JoVE 3264 Immunology and Infection