Csaba Fekete Laboratory of Integrative Neuroendocrinology Institute of Experimental Medicine Biography Publications Institution JoVE Articles Csaba Fekete has not added a biography. If you are Csaba Fekete and would like to personalize this page please email our Author Liaison for assistance. Publications Author Correction: A Previously Uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is Related to Evolutionary Adaptation, Energy Balance, and Kidney Physiology Nature Communications. Jun, 2023 | Pubmed ID: 37322005 A Previously Uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is Related to Evolutionary Adaptation, Energy Balance, and Kidney Physiology Nature Communications. May, 2023 | Pubmed ID: 37248239 Axonal T3 Uptake and Transport Can Trigger Thyroid Hormone Signaling in the Brain ELife. May, 2023 | Pubmed ID: 37204837 Unique, Specific CART Receptor-Independent Regulatory Mechanism of CART(55-102) Peptide in Spinal Nociceptive Transmission and Its Relation to Dipeptidyl-Peptidase 4 (DDP4) International Journal of Molecular Sciences. Jan, 2023 | Pubmed ID: 36674439 Different Hypothalamic Mechanisms Control Decreased Circulating Thyroid Hormone Levels in Infection and Fasting-Induced Non-Thyroidal Illness Syndrome in Male Thyroid Hormone Action Indicator Mice Thyroid : Official Journal of the American Thyroid Association. Jan, 2023 | Pubmed ID: 36322711 Tetrabromobisphenol A and Diclazuril Evoke Tissue-Specific Changes of Thyroid Hormone Signaling in Male Thyroid Hormone Action Indicator Mice International Journal of Molecular Sciences. Nov, 2022 | Pubmed ID: 36499108 Origin of Thyrotropin-releasing Hormone Neurons That Innervate the Tuberomammillary Nuclei Brain Structure & Function. Sep, 2022 | Pubmed ID: 35934753 The Metabolic Stress Response: Adaptation to Acute-, Repeated- and Chronic Challenges in Mice IScience. Aug, 2022 | Pubmed ID: 35880047 Triiodothyronine (T3) Promotes Brown Fat Hyperplasia Via Thyroid Hormone Receptor α Mediated Adipocyte Progenitor Cell Proliferation Nature Communications. Jun, 2022 | Pubmed ID: 35697700 Hypothalamic Nesfatin-1 Resistance May Underlie the Development of Type 2 Diabetes Mellitus in Maternally Undernourished Non-obese Rats Frontiers in Neuroscience. 2022 | Pubmed ID: 35386592 Pars Tuberalis As a Key Regulator of Neuroendocrine Functions Nature Reviews. Endocrinology. Jun, 2022 | Pubmed ID: 35361916 Tanycyte Specific Ablation of Diacylglycerol Lipase Alpha Stimulates the Hypothalamic-pituitary-thyroid Axis by Decreasing the Endocannabinoid Mediated Inhibition of TRH Release Journal of Neuroendocrinology. Jan, 2022 | Pubmed ID: 34970803 Expression of Glucagon-like Peptide 1 Receptor in Neuropeptide Y Neurons of the Arcuate Nucleus in Mice Brain Structure & Function. Jan, 2022 | Pubmed ID: 34596755 Distribution and Ultrastructural Localization of the Glucagon-like Peptide-1 Receptor (GLP-1R) in the Rat Brain Brain Structure & Function. Jan, 2021 | Pubmed ID: 33341919 Glucagon-Like Peptide-1 Regulates the Proopiomelanocortin Neurons of the Arcuate Nucleus Both Directly and Indirectly Via Presynaptic Action Neuroendocrinology. 2021 | Pubmed ID: 33152734 Semaglutide Lowers Body Weight in Rodents Via Distributed Neural Pathways JCI Insight. Mar, 2020 | Pubmed ID: 32213703 A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release Via the Endocannabinoid System IScience. Mar, 2020 | Pubmed ID: 32143135 Thyrotropin-Releasing-Hormone-Synthesizing Neurons of the Hypothalamic Paraventricular Nucleus Are Inhibited by Glycinergic Inputs Thyroid : Official Journal of the American Thyroid Association. Dec, 2019 | Pubmed ID: 31659941 Type 2 Deiodinase Polymorphism Causes ER Stress and Hypothyroidism in the Brain The Journal of Clinical Investigation. Jan, 2019 | Pubmed ID: 30352046 Chronic Amyloid β Oligomer Infusion Evokes Sustained Inflammation and Microglial Changes in the Rat Hippocampus Via NLRP3 Neuroscience. May, 2019 | Pubmed ID: 29522854 Transcellular Stomach Absorption of a Derivatized Glucagon-like Peptide-1 Receptor Agonist Science Translational Medicine. Nov, 2018 | Pubmed ID: 30429357 Endocannabinoid and Nitric Oxide Systems of the Hypothalamic Paraventricular Nucleus Mediate Effects of NPY on Energy Expenditure Molecular Metabolism. Dec, 2018 | Pubmed ID: 30274714 Estradiol Increases Glutamate and GABA Neurotransmission into GnRH Neurons Via Retrograde NO-Signaling in Proestrous Mice During the Positive Estradiol Feedback Period ENeuro. 2018 | Pubmed ID: 30079374 Glial Cell Type-specific Changes in Spinal Dipeptidyl Peptidase 4 Expression and Effects of Its Inhibitors in Inflammatory and Neuropatic Pain Scientific Reports. 02, 2018 | Pubmed ID: 29472575 Post Mortem Single-cell Labeling with DiI and Immunoelectron Microscopy Unveil the Fine Structure of Kisspeptin Neurons in Humans Brain Structure & Function. Jun, 2018 | Pubmed ID: 29380121 A Transgenic Mouse Model for Detection of Tissue-Specific Thyroid Hormone Action Endocrinology. Feb, 2018 | Pubmed ID: 29253128 Role of TRH/UCN3 Neurons of the Perifornical Area/bed Nucleus of Stria Terminalis Region in the Regulation of the Anorexigenic POMC Neurons of the Arcuate Nucleus in Male Mice and Rats Brain Structure & Function. Apr, 2018 | Pubmed ID: 29124350 Neuronal Connections of the Central Amygdalar Nucleus with Refeeding-activated Brain Areas in Rats Brain Structure & Function. Jan, 2018 | Pubmed ID: 28852859 Transient Hypothyroidism Favors Oligodendrocyte Generation Providing Functional Remyelination in the Adult Mouse Brain ELife. Sep, 2017 | Pubmed ID: 28875931 Localization of Connexin 43 Gap Junctions and Hemichannels in Tanycytes of Adult Mice Brain Research. Oct, 2017 | Pubmed ID: 28803831 Variable Proopiomelanocortin Expression in Tanycytes of the Adult Rat Hypothalamus and Pituitary Stalk The Journal of Comparative Neurology. Feb, 2017 | Pubmed ID: 27503597 Glucagon-Like Peptide-1 Excites Firing and Increases GABAergic Miniature Postsynaptic Currents (mPSCs) in Gonadotropin-Releasing Hormone (GnRH) Neurons of the Male Mice Via Activation of Nitric Oxide (NO) and Suppression of Endocannabinoid Signaling Pathways Frontiers in Cellular Neuroscience. 2016 | Pubmed ID: 27672360 Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice Endocrinology. Sep, 2016 | Pubmed ID: 27501182 Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function Cell Metabolism. May, 2016 | Pubmed ID: 27133129 Elucidation of the Anatomy of a Satiety Network: Focus on Connectivity of the Parabrachial Nucleus in the Adult Rat The Journal of Comparative Neurology. Oct, 2016 | Pubmed ID: 26918800 Altered Gene Expression Profiles of the Hypothalamic Arcuate Nucleus of Male Mice Suggest Profound Developmental Changes in Peptidergic Signaling Neuroendocrinology. 2016 | Pubmed ID: 26338351 Perinatal Deiodinase 2 Expression in Hepatocytes Defines Epigenetic Susceptibility to Liver Steatosis and Obesity Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26508642 Area-specific Analysis of the Distribution of Hypothalamic Neurons Projecting to the Rat Ventral Tegmental Area, with Special Reference to the GABAergic and Glutamatergic Efferents Frontiers in Neuroanatomy. 2015 | Pubmed ID: 26388742 Parallel Regulation of Thyroid Hormone Transporters OATP1c1 and MCT8 During and After Endotoxemia at the Blood-brain Barrier of Male Rodents Endocrinology. Apr, 2015 | Pubmed ID: 25594699 Prevalent Polymorphism in Thyroid Hormone-activating Enzyme Leaves a Genetic Fingerprint That Underlies Associated Clinical Syndromes The Journal of Clinical Endocrinology and Metabolism. Mar, 2015 | Pubmed ID: 25569702 Central Regulation of Hypothalamic-pituitary-thyroid Axis Under Physiological and Pathophysiological Conditions Endocrine Reviews. Apr, 2014 | Pubmed ID: 24423980 The CB1 Receptor Mediates the Peripheral Effects of Ghrelin on AMPK Activity but Not on Growth Hormone Release FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2013 | Pubmed ID: 23982145 CB1 Receptor Mediates the Effects of Glucocorticoids on AMPK Activity in the Hypothalamus The Journal of Endocrinology. Oct, 2013 | Pubmed ID: 23884964 Coordination of Hypothalamic and Pituitary T3 Production Regulates TSH Expression The Journal of Clinical Investigation. Apr, 2013 | Pubmed ID: 23524969 Thyrotropin-releasing Hormone-containing Axons Innervate Histaminergic Neurons in the Tuberomammillary Nucleus Brain Research. Dec, 2012 | Pubmed ID: 23063458 A Novel Pathway Regulates Thyroid Hormone Availability in Rat and Human Hypothalamic Neurosecretory Neurons PloS One. 2012 | Pubmed ID: 22719854 Refeeding-activated Glutamatergic Neurons in the Hypothalamic Paraventricular Nucleus (PVN) Mediate Effects of Melanocortin Signaling in the Nucleus Tractus Solitarius (NTS) Endocrinology. Aug, 2012 | Pubmed ID: 22700769 Distribution of Type 1 Cannabinoid Receptor-expressing Neurons in the Septal-hypothalamic Region of the Mouse: Colocalization with GABAergic and Glutamatergic Markers The Journal of Comparative Neurology. Apr, 2012 | Pubmed ID: 21935941 Retrograde Endocannabinoid Signaling Reduces GABAergic Synaptic Transmission to Gonadotropin-releasing Hormone Neurons Endocrinology. Dec, 2010 | Pubmed ID: 20926585 Distribution of Hypophysiotropic Thyrotropin-releasing Hormone (TRH)-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus of the Mouse The Journal of Comparative Neurology. Oct, 2010 | Pubmed ID: 20737594 Contribution of TNF-alpha and Nuclear Factor-kappaB Signaling to Type 2 Iodothyronine Deiodinase Activation in the Mediobasal Hypothalamus After Lipopolysaccharide Administration Endocrinology. Aug, 2010 | Pubmed ID: 20501675 Distribution and Axonal Projections of Neurons Coexpressing Thyrotropin-releasing Hormone and Urocortin 3 in the Rat Brain The Journal of Comparative Neurology. Dec, 2009 | Pubmed ID: 19844978 The E3 Ubiquitin Ligase TEB4 Mediates Degradation of Type 2 Iodothyronine Deiodinase Molecular and Cellular Biology. Oct, 2009 | Pubmed ID: 19651899 Noradrenergic Innervation of Hypophysiotropic Thyrotropin-releasing Hormone-synthesizing Neurons in Rats Brain Research. Oct, 2009 | Pubmed ID: 19651110 Improved Method for Combination of Immunocytochemistry and Nissl Staining Journal of Neuroscience Methods. Oct, 2009 | Pubmed ID: 19615409 Efferent Projections of Thyrotropin-releasing Hormone-synthesizing Neurons Residing in the Anterior Parvocellular Subdivision of the Hypothalamic Paraventricular Nucleus The Journal of Comparative Neurology. Jul, 2009 | Pubmed ID: 19425088 Tanycyte Pyroglutamyl Peptidase II Contributes to Regulation of the Hypothalamic-pituitary-thyroid Axis Through Glial-axonal Associations in the Median Eminence Endocrinology. May, 2009 | Pubmed ID: 19179432 Type 1 Cannabinoid Receptor-containing Axons Innervate Hypophysiotropic Thyrotropin-releasing Hormone-synthesizing Neurons Endocrinology. Jan, 2009 | Pubmed ID: 18818298 Peripheral, but Not Central, CB1 Antagonism Provides Food Intake-independent Metabolic Benefits in Diet-induced Obese Rats Diabetes. Nov, 2008 | Pubmed ID: 18716045 Differential Effects of Refeeding on Melanocortin-responsive Neurons in the Hypothalamic Paraventricular Nucleus Endocrinology. Sep, 2008 | Pubmed ID: 18467436 The Orexigenic Effect of Ghrelin is Mediated Through Central Activation of the Endogenous Cannabinoid System PloS One. Mar, 2008 | Pubmed ID: 18335063 Induction of Type 2 Iodothyronine Deiodinase in the Mediobasal Hypothalamus by Bacterial Lipopolysaccharide: Role of Corticosterone Endocrinology. May, 2008 | Pubmed ID: 18218695 Mitogen-activated Protein Kinase Contributes to Lipopolysaccharide-induced Activation of Corticotropin-releasing Hormone Synthesizing Neurons in the Hypothalamic Paraventricular Nucleus Endocrinology. May, 2008 | Pubmed ID: 18187539 Contribution of Noradrenergic and Adrenergic Cell Groups of the Brainstem and Agouti-related Protein-synthesizing Neurons of the Arcuate Nucleus to Neuropeptide-y Innervation of Corticotropin-releasing Hormone Neurons in Hypothalamic Paraventricular Nucleus of the Rat Endocrinology. Nov, 2007 | Pubmed ID: 17690163 Expression Patterns of WSB-1 and USP-33 Underlie Cell-specific Posttranslational Control of Type 2 Deiodinase in the Rat Brain Endocrinology. Oct, 2007 | Pubmed ID: 17628004 Negative Feedback Regulation of Hypophysiotropic Thyrotropin-releasing Hormone (TRH) Synthesizing Neurons: Role of Neuronal Afferents and Type 2 Deiodinase Frontiers in Neuroendocrinology. 2007 | Pubmed ID: 17588648 Cocaine- and Amphetamine-regulated Transcript (CART) is Colocalized with the Orexigenic Neuropeptide Y and Agouti-related Protein and Absent from the Anorexigenic Alpha-melanocyte-stimulating Hormone Neurons in the Infundibular Nucleus of the Human Hypothalamus Endocrinology. Sep, 2007 | Pubmed ID: 17525122 Distribution of Type 1 Cannabinoid Receptor (CB1)-immunoreactive Axons in the Mouse Hypothalamus The Journal of Comparative Neurology. Jul, 2007 | Pubmed ID: 17492633 Cocaine- and Amphetamine-regulated Transcript (CART) Expression is Differentially Regulated in the Hypothalamic Paraventricular Nucleus of Lactating Rats Exposed to Suckling or Cold Stimulation Brain Research. Feb, 2007 | Pubmed ID: 17174283 Distribution of Ghrelin-immunoreactive Neuronal Networks in the Human Hypothalamus Brain Research. Dec, 2006 | Pubmed ID: 17113048 Enhanced PIP3 Signaling in POMC Neurons Causes KATP Channel Activation and Leads to Diet-sensitive Obesity The Journal of Clinical Investigation. Jul, 2006 | Pubmed ID: 16794735 Neuroendocrine Implications for the Association Between Cocaine- and Amphetamine Regulated Transcript (CART) and Hypophysiotropic Thyrotropin-releasing Hormone (TRH) Peptides. Aug, 2006 | Pubmed ID: 16730860 Characterization of the Nuclear Factor-kappa B Responsiveness of the Human Dio2 Gene Endocrinology. Sep, 2006 | Pubmed ID: 16728495 Expression of Vesicular Glutamate Transporter-2 in Gonadotrope and Thyrotrope Cells of the Rat Pituitary. Regulation by Estrogen and Thyroid Hormone Status Endocrinology. Aug, 2006 | Pubmed ID: 16675529 Interconnection Between Orexigenic Neuropeptide Y- and Anorexigenic Alpha-melanocyte Stimulating Hormone-synthesizing Neuronal Systems of the Human Hypothalamus Brain Research. Mar, 2006 | Pubmed ID: 16473335 Origin of Cocaine- and Amphetamine-regulated Transcript-containing Axons Innervating Hypophysiotropic Corticotropin-releasing Hormone-synthesizing Neurons in the Rat Endocrinology. Jul, 2005 | Pubmed ID: 15831569 Glutamatergic Innervation of Corticotropin-releasing Hormone- and Thyrotropin-releasing Hormone-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus of the Rat Brain Research. Mar, 2005 | Pubmed ID: 15781046 Hypophysiotropic Thyrotropin-releasing Hormone and Corticotropin-releasing Hormone Neurons of the Rat Contain Vesicular Glutamate Transporter-2 Endocrinology. Jan, 2005 | Pubmed ID: 15486233 Ontogenic Redistribution of Type 2 Deiodinase Messenger Ribonucleic Acid in the Brain of Chicken Endocrinology. Aug, 2004 | Pubmed ID: 15087435 Medullary Adrenergic Neurons Contribute to the Cocaine- and Amphetamine-regulated Transcript-immunoreactive Innervation of Thyrotropin-releasing Hormone Synthesizing Neurons in the Hypothalamic Paraventricular Nucleus Brain Research. Apr, 2004 | Pubmed ID: 15047018 Galanin- but Not Galanin-like Peptide-containing Axon Terminals Innervate Hypophysiotropic TRH-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus Brain Research. Mar, 2004 | Pubmed ID: 14988032 Origin of Cocaine- and Amphetamine-regulated Transcript (CART)-immunoreactive Innervation of the Hypothalamic Paraventricular Nucleus The Journal of Comparative Neurology. Feb, 2004 | Pubmed ID: 14730586 Lipopolysaccharide Induces Type 2 Iodothyronine Deiodinase in the Mediobasal Hypothalamus: Implications for the Nonthyroidal Illness Syndrome Endocrinology. Apr, 2004 | Pubmed ID: 14684601 Origin of Neuropeptide Y-containing Afferents to Gonadotropin-releasing Hormone Neurons in Male Mice Endocrinology. Nov, 2003 | Pubmed ID: 12960087 Histamine-immunoreactive Neurons of the Tuberomammillary Nucleus Are Innervated by Alpha-melanocyte Stimulating Hormone-containing Axons. Generation of a New Histamine Antiserum for Ultrastructural Studies Brain Research. Apr, 2003 | Pubmed ID: 12676366 Neuropeptide Y1 and Y5 Receptors Mediate the Effects of Neuropeptide Y on the Hypothalamic-pituitary-thyroid Axis Endocrinology. Dec, 2002 | Pubmed ID: 12446577 GABA-ergic Innervation of Thyrotropin-releasing Hormone-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus of the Rat Brain Research. Dec, 2002 | Pubmed ID: 12445967 Agouti-related Protein (AGRP) Has a Central Inhibitory Action on the Hypothalamic-pituitary-thyroid (HPT) Axis; Comparisons Between the Effect of AGRP and Neuropeptide Y on Energy Homeostasis and the HPT Axis Endocrinology. Oct, 2002 | Pubmed ID: 12239096 VGF is Required for Obesity Induced by Diet, Gold Thioglucose Treatment, and Agouti and is Differentially Regulated in Pro-opiomelanocortin- and Neuropeptide Y-containing Arcuate Neurons in Response to Fasting The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2002 | Pubmed ID: 12177191 Medullary Adrenergic Neurons Contribute to the Neuropeptide Y-ergic Innervation of Hypophysiotropic Thyrotropin-releasing Hormone-synthesizing Neurons in the Rat Neuroscience Letters. May, 2002 | Pubmed ID: 11983297 Corticotropin-releasing Hormone-synthesizing Neurons of the Human Hypothalamus Receive Neuropeptide Y-immunoreactive Innervation from Neurons Residing Primarily Outside the Infundibular Nucleus The Journal of Comparative Neurology. May, 2002 | Pubmed ID: 11932939 Association of Cocaine- and Amphetamine-regulated Transcript-immunoreactive Elements with Thyrotropin-releasing Hormone-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus and Its Role in the Regulation of the Hypothalamic-pituitary-thyroid Axis During Fasting The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2000 | Pubmed ID: 11125000 Alpha-Melanocyte-stimulating Hormone is Contained in Nerve Terminals Innervating Thyrotropin-releasing Hormone-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus and Prevents Fasting-induced Suppression of Prothyrotropin-releasing Hormone Gene Expression The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2000 | Pubmed ID: 10662844 In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse Richárd Sinkó1,2, Petra Mohácsik1, Csaba Fekete*3, Balázs Gereben*1 1Laboratory of Molecular Cell Metabolism, Institute of Experimental Medicine, 2János Szentágothai PhD School of Neurosciences, Semmelweis University, 3Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine JoVE 65657 Neuroscience
In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse Richárd Sinkó1,2, Petra Mohácsik1, Csaba Fekete*3, Balázs Gereben*1 1Laboratory of Molecular Cell Metabolism, Institute of Experimental Medicine, 2János Szentágothai PhD School of Neurosciences, Semmelweis University, 3Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine JoVE 65657 Neuroscience