In JoVE (1)
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Articles by Ellen M. Sheffer in JoVE
The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders Tuan D. Tran1,2, Aenia Amin1,2, Keith G. Jones2, Ellen M. Sheffer1, Lidia Ortega1, Keith Dolman2 1Department of Psychology, East Carolina University, 2Multidisciplinary Studies Program in Neuroscience, East Carolina University Trace eyeblink classical conditioning (ECC) was used to assess hippocampal-dependent associative learning in adult rats that were administered a high concentration (11.9% v/v) of alcohol during early neonatal brain development. In general, ECC procedures are sound diagnostic tools for detecting brain dysfunction across many psychological and biomedical settings.