Eric C. Greene Department of Biochemistry & Molecular Biophysics Columbia University Biography Publications Institution JoVE Articles Eric C. Greene has not added a biography. If you are Eric C. Greene and would like to personalize this page please email our Author Liaison for assistance. Publications Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment During Homologous Recombination Cell. Jun, 2020 | Pubmed ID: 32502392 Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA Molecular Cell. May, 2020 | Pubmed ID: 32445620 Structures and Single-molecule Analysis of Bacterial Motor Nuclease AdnAB Illuminate the Mechanism of DNA Double-strand Break Resection Proceedings of the National Academy of Sciences of the United States of America. 12, 2019 | Pubmed ID: 31740608 Single-molecule Visualization of Human BLM Helicase As It Acts Upon Double- and Single-stranded DNA Substrates Nucleic Acids Research. 12, 2019 | Pubmed ID: 31544923 Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast Molecular Cell. 12, 2019 | Pubmed ID: 31542296 Defining the Influence of Rad51 and Dmc1 Lineage-specific Amino Acids on Genetic Recombination Genes & Development. 09, 2019 | Pubmed ID: 31371435 The RecQ Helicase Sgs1 Drives ATP-dependent Disruption of Rad51 Filaments Nucleic Acids Research. 05, 2019 | Pubmed ID: 30916344 Helicase Mechanisms During Homologous Recombination in Annual Review of Biophysics. 05, 2019 | Pubmed ID: 30857400 Regulatory Control of Sgs1 and Dna2 During Eukaryotic DNA End Resection Proceedings of the National Academy of Sciences of the United States of America. 03, 2019 | Pubmed ID: 30850524 Dynamic Interactions of the Homologous Pairing 2 (Hop2)-meiotic Nuclear Divisions 1 (Mnd1) Protein Complex with Meiotic Presynaptic Filaments in Budding Yeast The Journal of Biological Chemistry. 01, 2019 | Pubmed ID: 30420424 The Biochemistry of Early Meiotic Recombination Intermediates Cell Cycle (Georgetown, Tex.). 2018 | Pubmed ID: 30482074 New Roles for RAD52 in DNA Repair Cell Research. 12, 2018 | Pubmed ID: 30367126 Meiosis-specific Recombinase Dmc1 is a Potent Inhibitor of the Srs2 Antirecombinase Proceedings of the National Academy of Sciences of the United States of America. 10, 2018 | Pubmed ID: 30301803 Biochemical Attributes of Mitotic and Meiotic Presynaptic Complexes DNA Repair. 11, 2018 | Pubmed ID: 30195641 Single-Stranded DNA Curtains for Studying the Srs2 Helicase Using Total Internal Reflection Fluorescence Microscopy Methods in Enzymology. 2018 | Pubmed ID: 29458768 Regulation of Hed1 and Rad54 Binding During Maturation of the Meiosis-specific Presynaptic Complex The EMBO Journal. 04, 2018 | Pubmed ID: 29444896 Spontaneous Self-segregation of Rad51 and Dmc1 DNA Recombinases Within Mixed Recombinase Filaments The Journal of Biological Chemistry. 03, 2018 | Pubmed ID: 29382724 A Change of View: Homologous Recombination at Single-molecule Resolution Nature Reviews. Genetics. 04, 2018 | Pubmed ID: 29225334 Dissociation of Rad51 Presynaptic Complexes and Heteroduplex DNA Joints by Tandem Assemblies of Srs2 Cell Reports. Dec, 2017 | Pubmed ID: 29241544 Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation Cell Reports. Oct, 2017 | Pubmed ID: 29045827 BRCA1-BARD1 Promotes RAD51-mediated Homologous DNA Pairing Nature. 10, 2017 | Pubmed ID: 28976962 Monitoring Replication Protein A (RPA) Dynamics in Homologous Recombination Through Site-specific Incorporation of Non-canonical Amino Acids Nucleic Acids Research. Sep, 2017 | Pubmed ID: 28934470 The Condensin Complex is a Mechanochemical Motor That Translocates Along DNA Science (New York, N.Y.). 11, 2017 | Pubmed ID: 28882993 Sequential Eviction of Crowded Nucleoprotein Complexes by the Exonuclease RecBCD Molecular Motor Proceedings of the National Academy of Sciences of the United States of America. 08, 2017 | Pubmed ID: 28716908 Human RAD52 Interactions with Replication Protein A and the RAD51 Presynaptic Complex The Journal of Biological Chemistry. 07, 2017 | Pubmed ID: 28551686 Sequence Imperfections and Base Triplet Recognition by the Rad51/RecA Family of Recombinases The Journal of Biological Chemistry. 06, 2017 | Pubmed ID: 28476890 Replication Protein A Blocks the Way Biochemistry. 04, 2017 | Pubmed ID: 28333436 Telomere Recognition and Assembly Mechanism of Mammalian Shelterin Cell Reports. 01, 2017 | Pubmed ID: 28052260 Protein Dynamics of Human RPA and RAD51 on SsDNA During Assembly and Disassembly of the RAD51 Filament Nucleic Acids Research. 01, 2017 | Pubmed ID: 27903895 A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling Molecular Cell. 12, 2016 | Pubmed ID: 27867009 ATP Hydrolysis Promotes Duplex DNA Release by the RecA Presynaptic Complex The Journal of Biological Chemistry. Oct, 2016 | Pubmed ID: 27587394 Generalized Nucleation and Looping Model for Epigenetic Memory of Histone Modifications Proceedings of the National Academy of Sciences of the United States of America. 07, 2016 | Pubmed ID: 27382173 DNA Sequence Alignment During Homologous Recombination The Journal of Biological Chemistry. May, 2016 | Pubmed ID: 27129270 Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin Cell Reports. 05, 2016 | Pubmed ID: 27117417 Visualizing Recombination Intermediates with Single-stranded DNA Curtains Methods (San Diego, Calif.). 08, 2016 | Pubmed ID: 27038747 On the Influence of Protein-DNA Register During Homologous Recombination Cell Cycle (Georgetown, Tex.). 2016 | Pubmed ID: 26652653 Surveillance and Processing of Foreign DNA by the Escherichia Coli CRISPR-Cas System Cell. Nov, 2015 | Pubmed ID: 26522594 DNA RECOMBINATION. Base Triplet Stepping by the Rad51/RecA Family of Recombinases Science (New York, N.Y.). Aug, 2015 | Pubmed ID: 26315438 The Dynamics of Eukaryotic Replication Initiation: Origin Specificity, Licensing, and Firing at the Single-molecule Level Molecular Cell. May, 2015 | Pubmed ID: 25921072 A Molecular Take on Aesop's The Oak and the Reeds Cell. Mar, 2015 | Pubmed ID: 25768898 DNA Sequence Alignment by Microhomology Sampling During Homologous Recombination Cell. Feb, 2015 | Pubmed ID: 25684365 Protein Dynamics During Presynaptic-complex Assembly on Individual Single-stranded DNA Molecules Nature Structural & Molecular Biology. Oct, 2014 | Pubmed ID: 25195049 DNA Curtains: Novel Tools for Imaging Protein-nucleic Acid Interactions at the Single-molecule Level Methods in Cell Biology. 2014 | Pubmed ID: 24974030 Single-molecule Imaging of FtsK Translocation Reveals Mechanistic Features of Protein-protein Collisions on DNA Molecular Cell. Jun, 2014 | Pubmed ID: 24768536 RPA Antagonizes Microhomology-mediated Repair of DNA Double-strand Breaks Nature Structural & Molecular Biology. Apr, 2014 | Pubmed ID: 24608368 Visualizing Protein Movement on DNA at the Single-molecule Level Using DNA Curtains DNA Repair. Aug, 2014 | Pubmed ID: 24598576 Concentration-dependent Exchange of Replication Protein A on Single-stranded DNA Revealed by Single-molecule Imaging PloS One. 2014 | Pubmed ID: 24498402 DNA Interrogation by the CRISPR RNA-guided Endonuclease Cas9 Nature. Mar, 2014 | Pubmed ID: 24476820 DNA Dynamics and Single-molecule Biology Chemical Reviews. Mar, 2014 | Pubmed ID: 24400809 How Do Proteins Locate Specific Targets in DNA? Chemical Physics Letters. May, 2013 | Pubmed ID: 24187380 Tension Modulates Actin Filament Polymerization Mediated by Formin and Profilin Proceedings of the National Academy of Sciences of the United States of America. Jun, 2013 | Pubmed ID: 23716666 Molecular Traffic Jams on DNA Annual Review of Biophysics. 2013 | Pubmed ID: 23451891 Target Search Dynamics During Post-replicative Mismatch Repair Cell Cycle (Georgetown, Tex.). Feb, 2013 | Pubmed ID: 23343769 Towards Physiological Complexity with in Vitro Single-molecule Biophysics Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Feb, 2013 | Pubmed ID: 23267187 The Promoter-search Mechanism of Escherichia Coli RNA Polymerase is Dominated by Three-dimensional Diffusion Nature Structural & Molecular Biology. Feb, 2013 | Pubmed ID: 23262491 Sliding to the Rescue of Damaged DNA ELife. Dec, 2012 | Pubmed ID: 23240090 Single-molecule Imaging Reveals Target-search Mechanisms During DNA Mismatch Repair Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23012240 Measuring Intermolecular Rupture Forces with a Combined TIRF-optical Trap Microscope and DNA Curtains Biochemical and Biophysical Research Communications. Oct, 2012 | Pubmed ID: 22967893 Single-stranded DNA Curtains for Real-time Single-molecule Visualization of Protein-nucleic Acid Interactions Analytical Chemistry. Sep, 2012 | Pubmed ID: 22950646 The Unstructured Linker Arms of Mlh1-Pms1 Are Important for Interactions with DNA During Mismatch Repair Journal of Molecular Biology. Sep, 2012 | Pubmed ID: 22659005 Single-molecule Imaging of DNA Curtains Reveals Mechanisms of KOPS Sequence Targeting by the DNA Translocase FtsK Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22493241 Assembly of Recombinant Nucleosomes on Nanofabricated DNA Curtains for Single-molecule Imaging Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21809211 Supported Lipid Bilayers and DNA Curtains for High-throughput Single-molecule Studies Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21660710 Analyses of the Yeast Rad51 Recombinase A265V Mutant Reveal Different in Vivo Roles of Swi2-like Factors Nucleic Acids Research. Aug, 2011 | Pubmed ID: 21558173 Single-molecule Studies of Transcription: from One RNA Polymerase at a Time to the Gene Expression Profile of a Cell Journal of Molecular Biology. Oct, 2011 | Pubmed ID: 21255583 Single-molecule Imaging Reveals Mechanisms of Protein Disruption by a DNA Translocase Nature. Dec, 2010 | Pubmed ID: 21107319 Visualizing One-dimensional Diffusion of Eukaryotic DNA Repair Factors Along a Chromatin Lattice Nature Structural & Molecular Biology. Aug, 2010 | Pubmed ID: 20657586 DNA Curtains for High-throughput Single-molecule Optical Imaging Methods in Enzymology. 2010 | Pubmed ID: 20580969 Nanofabricated Racks of Aligned and Anchored DNA Substrates for Single-molecule Imaging Langmuir : the ACS Journal of Surfaces and Colloids. Jan, 2010 | Pubmed ID: 19736980 XPD Helicase Speeds Through a Molecular Traffic Jam Molecular Cell. Sep, 2009 | Pubmed ID: 19748351 Functional Significance of the Rad51-Srs2 Complex in Rad51 Presynaptic Filament Disruption Nucleic Acids Research. Nov, 2009 | Pubmed ID: 19745052 Single-molecule Imaging of DNA Curtains Reveals Intrinsic Energy Landscapes for Nucleosome Deposition Nature Structural & Molecular Biology. Oct, 2009 | Pubmed ID: 19734899 Structural Transitions Within Human Rad51 Nucleoprotein Filaments Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19622740 Visualizing the Disassembly of S. Cerevisiae Rad51 Nucleoprotein Filaments Journal of Molecular Biology. May, 2009 | Pubmed ID: 19327367 Functional Interactions of Meiotic Recombination Factors Rdh54 and Dmc1 DNA Repair. Feb, 2009 | Pubmed ID: 19028606 Single Molecule Studies of Homologous Recombination Molecular BioSystems. Nov, 2008 | Pubmed ID: 18931785 Parallel Arrays of Geometric Nanowells for Assembling Curtains of DNA with Controlled Lateral Dispersion Langmuir : the ACS Journal of Surfaces and Colloids. Oct, 2008 | Pubmed ID: 18788761 DNA Curtains and Nanoscale Curtain Rods: High-throughput Tools for Single Molecule Imaging Langmuir : the ACS Journal of Surfaces and Colloids. Sep, 2008 | Pubmed ID: 18683960 The Importance of Surfaces in Single-molecule Bioscience Molecular BioSystems. May, 2008 | Pubmed ID: 18414737 ATP-dependent Chromatin Remodeling by the Saccharomyces Cerevisiae Homologous Recombination Factor Rdh54 The Journal of Biological Chemistry. Apr, 2008 | Pubmed ID: 18292093 Dynamic Basis for One-dimensional DNA Scanning by the Mismatch Repair Complex Msh2-Msh6 Molecular Cell. Nov, 2007 | Pubmed ID: 17996701 A DNA-translocating Snf2 Molecular Motor: Saccharomyces Cerevisiae Rdh54 Displays Processive Translocation and Extrudes DNA Loops Journal of Molecular Biology. Jun, 2007 | Pubmed ID: 17467735 Visualizing the Assembly of Human Rad51 Filaments on Double-stranded DNA Journal of Molecular Biology. Oct, 2006 | Pubmed ID: 16979659 Visualizing the Behavior of Human Rad51 at the Single-molecule Level Cell Cycle (Georgetown, Tex.). May, 2006 | Pubmed ID: 16687937 Long-distance Lateral Diffusion of Human Rad51 on Double-stranded DNA Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16432240 Organized Arrays of Individual DNA Molecules Tethered to Supported Lipid Bilayers Langmuir : the ACS Journal of Surfaces and Colloids. Jan, 2006 | Pubmed ID: 16378434 DNA Curtains Shed Light on Complex Molecular Systems During Homologous Recombination Aviv Meir*1, Muwen Kong*1, Chaoyou Xue1, Eric C. Greene1 1Department of Biochemistry & Molecular Biophysics, Columbia University JoVE 61320 Genetics
DNA Curtains Shed Light on Complex Molecular Systems During Homologous Recombination Aviv Meir*1, Muwen Kong*1, Chaoyou Xue1, Eric C. Greene1 1Department of Biochemistry & Molecular Biophysics, Columbia University JoVE 61320 Genetics