Evangelos D. Michelakis Biography Publications JoVE Articles Evangelos D. Michelakis has not added a biography. If you are Evangelos D. Michelakis and would like to personalize this page please email our Author Liaison for assistance. Publications Pyruvate Dehydrogenase Inhibition by the Inflammatory Cytokine TNFα Contributes to the Pathogenesis of Pulmonary Arterial Hypertension Journal of Molecular Medicine (Berlin, Germany). Aug, 2011 | Pubmed ID: 21809123 The Role of Nogo and the Mitochondria-endoplasmic Reticulum Unit in Pulmonary Hypertension Science Translational Medicine. Jun, 2011 | Pubmed ID: 21697531 Chest. May, 2011 | Pubmed ID: 21540210 Journal of Molecular Medicine (Berlin, Germany). Oct, 2010 | Pubmed ID: 20734021 Fatty Acid Oxidation and Malonyl-CoA Decarboxylase in the Vascular Remodeling of Pulmonary Hypertension Science Translational Medicine. Aug, 2010 | Pubmed ID: 20702857 Chest. Jun, 2010 | Pubmed ID: 20522585 Current Opinion in Cardiology. Mar, 2010 | Pubmed ID: 20130456 The New England Journal of Medicine. Nov, 2009 | Pubmed ID: 19890129 Circulation. Sep, 2009 | Pubmed ID: 19752350 Dehydroepiandrosterone Reverses Systemic Vascular Remodeling Through the Inhibition of the Akt/GSK3-{beta}/NFAT Axis Circulation. Sep, 2009 | Pubmed ID: 19752325 Journal of the American College of Cardiology. Jun, 2009 | Pubmed ID: 19555853 American Journal of Physiology. Cell Physiology. Aug, 2009 | Pubmed ID: 19535513 American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2009 | Pubmed ID: 19411285 Circulation. Sep, 2008 | Pubmed ID: 18824655 American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2008 | Pubmed ID: 18621852 A Dynamic and Chamber-specific Mitochondrial Remodeling in Right Ventricular Hypertrophy Can Be Therapeutically Targeted The Journal of Thoracic and Cardiovascular Surgery. Jul, 2008 | Pubmed ID: 18603070 Circulation. May, 2008 | Pubmed ID: 18474822 Developmental Absence of the O2 Sensitivity of L-type Calcium Channels in Preterm Ductus Arteriosus Smooth Muscle Cells Impairs O2 Constriction Contributing to Patent Ductus Arteriosus Pediatric Research. Feb, 2008 | Pubmed ID: 18091358 CD36 Expression Contributes to Age-induced Cardiomyopathy in Mice Circulation. Nov, 2007 | Pubmed ID: 17967771 Statin Therapy, Alone or with Rapamycin, Does Not Reverse Monocrotaline Pulmonary Arterial Hypertension: the Rapamcyin-atorvastatin-simvastatin Study American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2007 | Pubmed ID: 17675370 Phosphodiesterase Type 5 is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility Circulation. Jul, 2007 | Pubmed ID: 17606845 The Nuclear Factor of Activated T Cells in Pulmonary Arterial Hypertension Can Be Therapeutically Targeted Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17596340 Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2007 | Pubmed ID: 17483441 Oxygen Activates the Rho/Rho-kinase Pathway and Induces RhoB and ROCK-1 Expression in Human and Rabbit Ductus Arteriosus by Increasing Mitochondria-derived Reactive Oxygen Species: a Newly Recognized Mechanism for Sustaining Ductal Constriction Circulation. Apr, 2007 | Pubmed ID: 17353442 A Mitochondria-K+ Channel Axis is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth Cancer Cell. Jan, 2007 | Pubmed ID: 17222789 American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2007 | Pubmed ID: 17142350 American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jan, 2007 | Pubmed ID: 16990484 Microcirculation (New York, N.Y. : 1994). Dec, 2006 | Pubmed ID: 17085423 Absence of Malonyl Coenzyme A Decarboxylase in Mice Increases Cardiac Glucose Oxidation and Protects the Heart from Ischemic Injury Circulation. Oct, 2006 | Pubmed ID: 17030679 Current Opinion in Cardiology. Jul, 2006 | Pubmed ID: 16755209 An Abnormal Mitochondrial-hypoxia Inducible Factor-1alpha-Kv Channel Pathway Disrupts Oxygen Sensing and Triggers Pulmonary Arterial Hypertension in Fawn Hooded Rats: Similarities to Human Pulmonary Arterial Hypertension Circulation. Jun, 2006 | Pubmed ID: 16735674 A Central Role for Oxygen-sensitive K+ Channels and Mitochondria in the Specialized Oxygen-sensing System Novartis Foundation Symposium. 2006 | Pubmed ID: 16686435 Circulation Research. Feb, 2006 | Pubmed ID: 16456109 Drugs & Aging. 2005 | Pubmed ID: 16245957 Vascular Endothelial Growth Factor Gene Therapy Increases Survival, Promotes Lung Angiogenesis, and Prevents Alveolar Damage in Hyperoxia-induced Lung Injury: Evidence That Angiogenesis Participates in Alveolarization Circulation. Oct, 2005 | Pubmed ID: 16230500 Gene Therapy Targeting Survivin Selectively Induces Pulmonary Vascular Apoptosis and Reverses Pulmonary Arterial Hypertension The Journal of Clinical Investigation. Jun, 2005 | Pubmed ID: 15931388 Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2005 | Pubmed ID: 15591309 Hypoxic Pulmonary Vasoconstriction: Redox Regulation of O2-sensitive K+ Channels by a Mitochondrial O2-sensor in Resistance Artery Smooth Muscle Cells Journal of Molecular and Cellular Cardiology. Dec, 2004 | Pubmed ID: 15572043 Dichloroacetate Prevents and Reverses Pulmonary Hypertension by Inducing Pulmonary Artery Smooth Muscle Cell Apoptosis Circulation Research. Oct, 2004 | Pubmed ID: 15375007 Oxygen-sensitive Kv Channel Gene Transfer Confers Oxygen Responsiveness to Preterm Rabbit and Remodeled Human Ductus Arteriosus: Implications for Infants with Patent Ductus Arteriosus Circulation. Sep, 2004 | Pubmed ID: 15353504 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2004 | Pubmed ID: 15333581 Preferential Expression and Function of Voltage-gated, O2-sensitive K+ Channels in Resistance Pulmonary Arteries Explains Regional Heterogeneity in Hypoxic Pulmonary Vasoconstriction: Ionic Diversity in Smooth Muscle Cells Circulation Research. Aug, 2004 | Pubmed ID: 15217912 O2 Sensing in the Human Ductus Arteriosus: Redox-sensitive K+ Channels Are Regulated by Mitochondria-derived Hydrogen Peroxide Biological Chemistry. Mar-Apr, 2004 | Pubmed ID: 15134333 Archives of Internal Medicine. Mar, 2004 | Pubmed ID: 15006828 Advances in Experimental Medicine and Biology. 2003 | Pubmed ID: 14713130 Circulation. Oct, 2003 | Pubmed ID: 14568893 In Vivo Gene Transfer of the O2-sensitive Potassium Channel Kv1.5 Reduces Pulmonary Hypertension and Restores Hypoxic Pulmonary Vasoconstriction in Chronically Hypoxic Rats Circulation. Apr, 2003 | Pubmed ID: 12695303 Heart Failure Reviews. Jan, 2003 | Pubmed ID: 12652155 Circulation. Feb, 2003 | Pubmed ID: 12578883 American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2002 | Pubmed ID: 12388256 O2 Sensing in the Human Ductus Arteriosus: Regulation of Voltage-gated K+ Channels in Smooth Muscle Cells by a Mitochondrial Redox Sensor Circulation Research. Sep, 2002 | Pubmed ID: 12242265 Circulation Research. Jun, 2002 | Pubmed ID: 12089069 Circulation. Jan, 2002 | Pubmed ID: 11790708 Human Internal Mammary Artery (IMA) Transplantation and Stenting: A Human Model to Study the Development of In-Stent Restenosis JoVE 3663 Medicine
Human Internal Mammary Artery (IMA) Transplantation and Stenting: A Human Model to Study the Development of In-Stent Restenosis JoVE 3663 Medicine
