James Hicks Department of Biological Sciences, Dornsife College of Letters, Arts, and Sciences University of Southern California Biography Publications Institution JoVE Articles James Hicks has not added a biography. If you are James Hicks and would like to personalize this page please email our Author Liaison for assistance. Publications Platelet-coated Circulating Tumor Cells Are a Predictive Biomarker in Patients with Metastatic Castrate Resistant Prostate Cancer Molecular Cancer Research : MCR. Aug, 2021 | Pubmed ID: 34462330 Inter-eye Genomic Heterogeneity in Bilateral Retinoblastoma Via Aqueous Humor Liquid Biopsy NPJ Precision Oncology. Jul, 2021 | Pubmed ID: 34316014 Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma Cancers. Jul, 2021 | Pubmed ID: 34283049 Establishing the Clinical Utility of CtDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy Cancers. Mar, 2021 | Pubmed ID: 33805776 Large Extracellular Vesicle Characterization and Association with Circulating Tumor Cells in Metastatic Castrate Resistant Prostate Cancer Cancers. Mar, 2021 | Pubmed ID: 33801459 N-Acetyl-L-cysteine Promotes Growth and Expansion of Single Circulating Tumor Cells by Mitigating Cellular Stress Responses Molecular Cancer Research : MCR. 03, 2021 | Pubmed ID: 33303691 Correction: Opportunities to Implement a Sustainable Genomic Medicine Program: Lessons Learned from the IGNITE Network Genetics in Medicine : Official Journal of the American College of Medical Genetics. Dec, 2020 | Pubmed ID: 33288881 Treatment Response and Tumor Evolution: Lessons from an Extended Series of Multianalyte Liquid Biopsies in a Metastatic Breast Cancer Patient Cold Spring Harbor Molecular Case Studies. 12, 2020 | Pubmed ID: 33203646 Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients Translational Vision Science & Technology. 09, 2020 | Pubmed ID: 33062393 Modeling the Onset of Symptoms of COVID-19 Frontiers in Public Health. 2020 | Pubmed ID: 32903584 Generic Protocols for the Analytical Validation of Next-Generation Sequencing-Based CtDNA Assays: A Joint Consensus Recommendation of the BloodPAC's Analytical Variables Working Group Clinical Chemistry. 09, 2020 | Pubmed ID: 32870995 Author Correction: SMURF-seq: Efficient Copy Number Profiling on Long-read Sequencers Genome Biology. Aug, 2020 | Pubmed ID: 32843071 Correction: Opportunities to Implement a Sustainable Genomic Medicine Program: Lessons Learned from the IGNITE Network Genetics in Medicine : Official Journal of the American College of Medical Genetics. Oct, 2020 | Pubmed ID: 32719393 Liquid Biopsy in Colorectal Carcinoma: Clinical Applications and Challenges Cancers. May, 2020 | Pubmed ID: 32471160 Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability As a Distinctive Feature of Aggressive Prostate Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 08, 2020 | Pubmed ID: 32341031 Whole-Exome Sequencing Analysis of the Progression from Non-Low-Grade Ductal Carcinoma to Invasive Ductal Carcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 07, 2020 | Pubmed ID: 32220886 Minimum Technical Data Elements for Liquid Biopsy Data Submitted to Public Databases Clinical Pharmacology and Therapeutics. 04, 2020 | Pubmed ID: 32017048 Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients The Journal of Molecular Diagnostics : JMD. 03, 2020 | Pubmed ID: 31978562 Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis Drivers Cancer Discovery. 01, 2020 | Pubmed ID: 31601552 Single Cell Correlation Analysis of Liquid and Solid Biopsies in Metastatic Colorectal Cancer Oncotarget. Dec, 2019 | Pubmed ID: 31903162 A Truncating Mutation in the Autophagy Gene UVRAG Drives Inflammation and Tumorigenesis in Mice Nature Communications. 12, 2019 | Pubmed ID: 31831743 Circulating Tumor Cells As a Response Monitor in Stage IV Non-small Cell Lung Cancer Journal of Translational Medicine. 08, 2019 | Pubmed ID: 31462312 SMURF-seq: Efficient Copy Number Profiling on Long-read Sequencers Genome Biology. 07, 2019 | Pubmed ID: 31287019 Single-Cell Analysis of Circulating Tumor Cells Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30649733 Single-Cell Applications of Next-Generation Sequencing Cold Spring Harbor Perspectives in Medicine. 10, 2019 | Pubmed ID: 30617056 Correction: Opportunities to Implement a Sustainable Genomic Medicine Program: Lessons Learned from the IGNITE Network Genetics in Medicine : Official Journal of the American College of Medical Genetics. Jul, 2019 | Pubmed ID: 30158693 Opportunities to Implement a Sustainable Genomic Medicine Program: Lessons Learned from the IGNITE Network Genetics in Medicine : Official Journal of the American College of Medical Genetics. 03, 2019 | Pubmed ID: 29997387 Clonal Diversity Revealed by Morphoproteomic and Copy Number Profiles of Single Prostate Cancer Cells at Diagnosis Convergent Science Physical Oncology. Mar, 2018 | Pubmed ID: 32670616 Multiplex Protein Detection on Circulating Tumor Cells from Liquid Biopsies Using Imaging Mass Cytometry Convergent Science Physical Oncology. Mar, 2018 | Pubmed ID: 30906572 Single-cell RNA-seq Analysis Identifies Markers of Resistance to Targeted BRAF Inhibitors in Melanoma Cell Populations Genome Research. 09, 2018 | Pubmed ID: 30061114 Improved Molecular Karyotyping in Glioblastoma Mutation Research. 09, 2018 | Pubmed ID: 30055482 When It Comes to Genomic Analysis of Tumours, Don't Buy in Bulk British Journal of Cancer. 05, 2018 | Pubmed ID: 29743553 Potential of Aqueous Humor As a Surrogate Tumor Biopsy for Retinoblastoma-Reply JAMA Ophthalmology. 05, 2018 | Pubmed ID: 29566117 Effect of Blood Collection Tube Type and Time to Processing on the Enumeration and High-Content Characterization of Circulating Tumor Cells Using the High-Definition Single-Cell Assay Archives of Pathology & Laboratory Medicine. Feb, 2018 | Pubmed ID: 29144792 Unravelling Biology and Shifting Paradigms in Cancer with Single-cell Sequencing Nature Reviews. Cancer. 08, 2017 | Pubmed ID: 28835719 Whole-genome Single-cell Copy Number Profiling from Formalin-fixed Paraffin-embedded Samples Nature Medicine. Mar, 2017 | Pubmed ID: 28165479 TGF-β Reduces DNA Ds-break Repair Mechanisms to Heighten Genetic Diversity and Adaptability of CD44+/CD24- Cancer Cells ELife. 01, 2017 | Pubmed ID: 28092266 Paired High-Content Analysis of Prostate Cancer Cells in Bone Marrow and Blood Characterizes Increased Androgen Receptor Expression in Tumor Cell Clusters Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2017 | Pubmed ID: 27702818 Vasculogenic Mimicry in Small Cell Lung Cancer Nature Communications. 11, 2016 | Pubmed ID: 27827359 Limited Genomic Heterogeneity of Circulating Melanoma Cells in Advanced Stage Patients Physical Biology. Jan, 2015 | Pubmed ID: 25574741 Rapid Phenotypic and Genomic Change in Response to Therapeutic Pressure in Prostate Cancer Inferred by High Content Analysis of Single Circulating Tumor Cells PloS One. 2014 | Pubmed ID: 25084170 The Maize Methylome Influences MRNA Splice Sites and Reveals Widespread Paramutation-like Switches Guided by Small RNA Genome Research. Oct, 2013 | Pubmed ID: 23739895 Updates to the RMAP Short-read Mapping Software Bioinformatics (Oxford, England). Nov, 2009 | Pubmed ID: 19736251 High Definition Profiling of Mammalian DNA Methylation by Array Capture and Single Molecule Bisulfite Sequencing Genome Research. Sep, 2009 | Pubmed ID: 19581485 Simultaneous Identification of Clinically Relevant Mutations and Copy Number Alterations in Aqueous Humor of Retinoblastoma Eyes Ophthalmic Genetics. | Pubmed ID: 32799607 Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival Molecular Cancer Research : MCR. | Pubmed ID: 32434859 Variability in Retinoblastoma Genome Stability is Driven by Age and Not Heritability Genes, Chromosomes & Cancer. | Pubmed ID: 32390242 Aqueous Humor Is Superior to Blood As a Liquid Biopsy for Retinoblastoma Ophthalmology. | Pubmed ID: 31767439 Genomic CfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma Molecular Cancer Research : MCR. | Pubmed ID: 30061186 Potential of Aqueous Humor As a Surrogate Tumor Biopsy for Retinoblastoma JAMA Ophthalmology. | Pubmed ID: 29049475 Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic Analysis Mary E. Kim1,2, Liya Xu1,2,3,11, Rishvanth K. Prabakar4, Lishuang Shen5, Chen-Ching Peng1,3, Peter Kuhn3,6,7,8, Xiaowu Gai5,9, James Hicks3,6,10, Jesse L. Berry1,2,6,11 1The Vision Center, Children’s Hospital Los Angeles, 2USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, 3Department of Biological Sciences, Dornsife College of Letters, Arts, and Sciences, University of Southern California, 4Department of Molecular and Computational Biology, University of Southern California, 5Center for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, 6Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 7Department of Aerospace and Mechanical Engineering, Viterbi School of Engineering, University of Southern California, 8Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, 9Department of Pathology and Laboratory Medicine, Keck School of Medicine of USC, 10Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, 11The Saban Research Institute, Children’s Hospital Los Angeles JoVE 62939 Cancer Research
Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic Analysis Mary E. Kim1,2, Liya Xu1,2,3,11, Rishvanth K. Prabakar4, Lishuang Shen5, Chen-Ching Peng1,3, Peter Kuhn3,6,7,8, Xiaowu Gai5,9, James Hicks3,6,10, Jesse L. Berry1,2,6,11 1The Vision Center, Children’s Hospital Los Angeles, 2USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, 3Department of Biological Sciences, Dornsife College of Letters, Arts, and Sciences, University of Southern California, 4Department of Molecular and Computational Biology, University of Southern California, 5Center for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, 6Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 7Department of Aerospace and Mechanical Engineering, Viterbi School of Engineering, University of Southern California, 8Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, 9Department of Pathology and Laboratory Medicine, Keck School of Medicine of USC, 10Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, 11The Saban Research Institute, Children’s Hospital Los Angeles JoVE 62939 Cancer Research