In JoVE (1)
Articles by Jeffrey Scott Pannell in JoVE
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations Robert C. Rennert1, Jeffrey A. Steinberg1, Vincent J. Cheung1, David R. Santiago-Dieppa1, Jeffrey Scott Pannell1, Alexander A. Khalessi1 1Department of Neurosurgery, University of California, San Diego Surgery is the gold standard for accessible arteriovenious malformations (AVMs), and pre-operative embolization can simplify this procedure. We describe our approach for staged endovascular embolization and open resection of AVMs, and provide a representative clinical example highlighting the advantages of a comprehensively trained neurovascular surgeon leading a multi-disciplinary clinical team.
Other articles by Jeffrey Scott Pannell on PubMed
Endothelial Trauma from Mechanical Thrombectomy in Acute Stroke: in Vitro Live-cell Platform with Animal Validation Stroke. Apr, 2015 | Pubmed ID: 25712942 Endovascular thrombectomy has shown promise for the treatment of acute strokes resulting from large-vessel occlusion. Reperfusion-related injury may contribute to the observed decoupling of angiographic and clinical outcomes. Iatrogenic disruption of the endothelium during thrombectomy is potentially a key mediator of this process that requires further study.
302 Vessel Wall Enhancement on Magnetic Resonance Imaging After Stent-Retriever Thrombectomy Neurosurgery. Aug, 2016 | Pubmed ID: 27399500 Animal and in vitro studies have demonstrated histologic iatrogenic endothelial injury after stent-retriever thrombectomy. However, noncontrast vessel wall magnetic resonance imaging (MRI) studies have failed to demonstrate vessel injury. Our prospective study examines iatrogenic endothelial damage after stent-retriever thrombectomy in vivo utilizing high-resolution contrast-enhanced vessel wall MRI (VW-MRI).