Mairene Coto-Llerena Visceral Surgery and Precision Medicine Research Laboratory, Department of Biomedicine University of Basel Biography Publications Institution JoVE Articles Mairene Coto-Llerena has not added a biography. If you are Mairene Coto-Llerena and would like to personalize this page please email our Author Liaison for assistance. Publications Patient-derived Organoids Identify Tailored Therapeutic Options and Determinants of Plasticity in Sarcomatoid Urothelial Bladder Cancer NPJ Precision Oncology. Nov, 2023 | Pubmed ID: 37919480 Arginine Reprograms Metabolism in Liver Cancer Via RBM39 Cell. Nov, 2023 | Pubmed ID: 37804830 Discovery of Synthetic Lethal Interactions from Large-scale Pan-cancer Perturbation Screens Nature Communications. Dec, 2022 | Pubmed ID: 36517508 Transposon-activated POU5F1B Promotes Colorectal Cancer Growth and Metastasis Nature Communications. Aug, 2022 | Pubmed ID: 35987910 The Role of Chronic Liver Diseases in the Emergence and Recurrence of Hepatocellular Carcinoma: An Omics Perspective Frontiers in Medicine. 2022 | Pubmed ID: 35814741 Patient-derived Tumor Organoids for Personalized Medicine in a Patient with Rare Hepatocellular Carcinoma with Neuroendocrine Differentiation: a Case Report Communications Medicine. 2022 | Pubmed ID: 35789568 Author Correction: GATA3 and MDM2 Are Synthetic Lethal in Estrogen Receptor-positive Breast Cancers Communications Biology. Jul, 2022 | Pubmed ID: 35787660 Genomic Analysis of Focal Nodular Hyperplasia with Associated Hepatocellular Carcinoma Unveils Its Malignant Potential: a Case Report Communications Medicine. 2022 | Pubmed ID: 35603298 Integrative Proteogenomic Characterization of Hepatocellular Carcinoma Across Etiologies and Stages Nature Communications. May, 2022 | Pubmed ID: 35508466 GATA3 and MDM2 Are Synthetic Lethal in Estrogen Receptor-positive Breast Cancers Communications Biology. Apr, 2022 | Pubmed ID: 35440675 Circulating Cell-Free DNA Captures the Intratumor Heterogeneity in Multinodular Hepatocellular Carcinoma JCO Precision Oncology. Mar, 2022 | Pubmed ID: 35263170 Epigenetic Priming in Chronic Liver Disease Impacts the Transcriptional and Genetic Landscapes of Hepatocellular Carcinoma Molecular Oncology. Feb, 2022 | Pubmed ID: 34863035 Standardizing Patient-Derived Organoid Generation Workflow to Avoid Microbial Contamination From Colorectal Cancer Tissues Frontiers in Oncology. 2021 | Pubmed ID: 35083141 Supervised Learning Based on Tumor Imaging and Biopsy Transcriptomics Predicts Response of Hepatocellular Carcinoma to Transarterial Chemoembolization Cell Reports. Medicine. Nov, 2021 | Pubmed ID: 34841291 YAP/TAZ and ATF4 Drive Resistance to Sorafenib in Hepatocellular Carcinoma by Preventing Ferroptosis EMBO Molecular Medicine. Dec, 2021 | Pubmed ID: 34664408 Interferon Lambda 4 Impairs Hepatitis C Viral Antigen Presentation and Attenuates T Cell Responses Nature Communications. Aug, 2021 | Pubmed ID: 34385466 Systematic Identification of Novel Cancer Genes Through Analysis of Deep ShRNA Perturbation Screens Nucleic Acids Research. Sep, 2021 | Pubmed ID: 34313788 USP29-mediated HIF1α Stabilization is Associated with Sorafenib Resistance of Hepatocellular Carcinoma Cells by Upregulating Glycolysis Oncogenesis. Jul, 2021 | Pubmed ID: 34272356 Transcriptional Enhancer Factor Domain Family Member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo-Independent Regulation of Heat Shock Protein 70 Family Members Hepatology Communications. Apr, 2021 | Pubmed ID: 33860124 Adenylosuccinate Lyase is Oncogenic in Colorectal Cancer by Causing Mitochondrial Dysfunction and Independent Activation of NRF2 and MTOR-MYC-axis Theranostics. 2021 | Pubmed ID: 33754045 Interferon Lambda 4 Can Directly Activate Human CD19 B Cells and CD8 T Cells Life Science Alliance. Jan, 2021 | Pubmed ID: 33158978 Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer Cancer Immunology Research. Nov, 2020 | Pubmed ID: 32839156 High Expression of FAP in Colorectal Cancer Is Associated With Angiogenesis and Immunoregulation Processes Frontiers in Oncology. 2020 | Pubmed ID: 32733792 A Pygopus 2-Histone Interaction Is Critical for Cancer Cell Dedifferentiation and Progression in Malignant Breast Cancer Cancer Research. Sep, 2020 | Pubmed ID: 32586983 Microbiota-induced Tissue Signals Regulate ILC3-mediated Antigen Presentation Nature Communications. Apr, 2020 | Pubmed ID: 32286285 Hepatocellular Carcinoma Xenografts Established From Needle Biopsies Preserve the Characteristics of the Originating Tumors Hepatology Communications. Jul, 2019 | Pubmed ID: 31334445 SOCS1 is an Inducible Negative Regulator of Interferon λ (IFN-λ)-induced Gene Expression The Journal of Biological Chemistry. Oct, 2017 | Pubmed ID: 28900038 A Hepatocellular Cancer Patient-derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth Fabian Haak*1, Gabriel Fridolin Hess*1, Philipp Sedlaczek1, Savas Deniz Soysal2, Jürg Vosbeck3, Salvatore Piscuoglio4,5, Mairene Coto-Llerena*4, Otto Kollmar*1 1Clarunis, Department of Visceral Surgery, University Center for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital Basel, 2Faculty of Medicine, University of Basel, 3Institute of Medical Genetics and Pathology, University Hospital Basel, 4Visceral Surgery and Precision Medicine Research Laboratory, Department of Biomedicine, University of Basel, 5IRCCS Humanitas Research Hospital JoVE 66245 Cancer Research
A Hepatocellular Cancer Patient-derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth Fabian Haak*1, Gabriel Fridolin Hess*1, Philipp Sedlaczek1, Savas Deniz Soysal2, Jürg Vosbeck3, Salvatore Piscuoglio4,5, Mairene Coto-Llerena*4, Otto Kollmar*1 1Clarunis, Department of Visceral Surgery, University Center for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital Basel, 2Faculty of Medicine, University of Basel, 3Institute of Medical Genetics and Pathology, University Hospital Basel, 4Visceral Surgery and Precision Medicine Research Laboratory, Department of Biomedicine, University of Basel, 5IRCCS Humanitas Research Hospital JoVE 66245 Cancer Research