Massoud Motamedi Biomedical Engineering and Imaging Sciences Group University of Texas Medical Branch Biography Publications Institution JoVE Articles Massoud Motamedi has not added a biography. If you are Massoud Motamedi and would like to personalize this page please email our Author Liaison for assistance. Publications Endoderm and Hepatic Progenitor Cells Engraft in the Quiescent Liver Concurrent with Intrinsically Activated Epithelial-to-Mesenchymal Transition Cell Transplantation. Jan-Dec, 2021 | Pubmed ID: 33657866 Surrogate Post-coital Testing for Contraceptive Efficacy Against Human Sperm Activity in the Ovine Vaginal Model† Biology of Reproduction. Feb, 2021 | Pubmed ID: 33300559 Liposomal 2-Methoxyestradiol Nanoparticles for Treatment of Uterine Leiomyoma in a Patient-Derived Xenograft Mouse Model Reproductive Sciences (Thousand Oaks, Calif.). Jan, 2021 | Pubmed ID: 32632769 Multispecies Evaluation of a Long-Acting Tenofovir Alafenamide Subdermal Implant for HIV Prophylaxis Frontiers in Pharmacology. 2020 | Pubmed ID: 33536904 Scattering Angle Resolved Optical Coherence Tomography Detects Early Changes in 3xTg Alzheimer's Disease Mouse Model Translational Vision Science & Technology. 04, 2020 | Pubmed ID: 32821490 Quantitative Optical Coherence Tomography Angiography Biomarkers in a Treat-and-Extend Dosing Regimen in Neovascular Age-Related Macular Degeneration Translational Vision Science & Technology. 02, 2020 | Pubmed ID: 32714644 Neuronal Epac1 Mediates Retinal Neurodegeneration in Mouse Models of Ocular Hypertension The Journal of Experimental Medicine. 04, 2020 | Pubmed ID: 31918438 Pharmacoproteomics Reveal Novel Protective Activity of Bromodomain Containing 4 Inhibitors on Vascular Homeostasis in TLR3-mediated Airway Remodeling Journal of Proteomics. 08, 2019 | Pubmed ID: 31195152 Long-Term Effect of Lactation on Maternal Cardiovascular Function and Adiposity in a Murine Model American Journal of Perinatology. 04, 2019 | Pubmed ID: 30193385 Efficacy of Novel Highly Specific Bromodomain-Containing Protein 4 Inhibitors in Innate Inflammation-Driven Airway Remodeling American Journal of Respiratory Cell and Molecular Biology. 01, 2019 | Pubmed ID: 30153047 AAV2-mediated GRP78 Transfer Alleviates Retinal Neuronal Injury by Downregulating ER Stress and Tau Oligomer Formation Investigative Ophthalmology & Visual Science. 09, 2018 | Pubmed ID: 30267089 Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy Aided by Tissue Optical Clearing Scientific Reports. 09, 2018 | Pubmed ID: 30190498 Noninvasive Allergic Sinus Congestion and Resolution Assessments Using Microcomputed Tomography Imaging Journal of Applied Physiology (Bethesda, Md. : 1985). 11, 2018 | Pubmed ID: 30161008 OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling EC Ophthalmology. 2017 | Pubmed ID: 29333536 Evaluation of Immunological Markers of Ovine Vaginal Irritation: Implications for Preclinical Assessment of Non-vaccine HIV Preventive Agents Journal of Reproductive Immunology. 11, 2017 | Pubmed ID: 29054075 Effects of Storage Temperature on Airway Exosome Integrity for Diagnostic and Functional Analyses Journal of Extracellular Vesicles. 2017 | Pubmed ID: 28819550 Critical Role of the CXCL10/C-X-C Chemokine Receptor 3 Axis in Promoting Leukocyte Recruitment and Neuronal Injury During Traumatic Optic Neuropathy Induced by Optic Nerve Crush The American Journal of Pathology. Feb, 2017 | Pubmed ID: 27960090 NF-κB Mediates Mesenchymal Transition, Remodeling, and Pulmonary Fibrosis in Response to Chronic Inflammation by Viral RNA Patterns American Journal of Respiratory Cell and Molecular Biology. 04, 2017 | Pubmed ID: 27911568 Topical Injury Evaluation of the Murine Colorectal Mucosa Using Confocal Endomicrosopy: a Valuable Method for Assessing Mucosal Injuries Associated with Risk of Pathogen Transmission Journal of Microscopy. 11, 2016 | Pubmed ID: 27351717 Early Breast Cancer Screening Using Iron/iron Oxide-based Nanoplatforms with Sub-femtomolar Limits of Detection Beilstein Journal of Nanotechnology. 2016 | Pubmed ID: 27335730 Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced Retinopathy Investigative Ophthalmology & Visual Science. 06, 2016 | Pubmed ID: 27273718 In Vivo Rectal Mucosal Barrier Function Imaging in a Large-Animal Model by Using Confocal Endomicroscopy: Implications for Injury Assessment and Use in HIV Prevention Studies Antimicrobial Agents and Chemotherapy. 08, 2016 | Pubmed ID: 27185807 High-fructose Diet in Pregnancy Leads to Fetal Programming of Hypertension, Insulin Resistance, and Obesity in Adult offspring American Journal of Obstetrics and Gynecology. 09, 2016 | Pubmed ID: 27060421 Elevated Testosterone Reduces Uterine Blood Flow, Spiral Artery Elongation, and Placental Oxygenation in Pregnant Rats Hypertension (Dallas, Tex. : 1979). Mar, 2016 | Pubmed ID: 26781277 Development of a Novel Imaging System for Cell Therapy in the Brain Stem Cell Research & Therapy. Jul, 2015 | Pubmed ID: 26194790 Novel Effects of Simvastatin on Uterine Fibroid Tumors: in Vitro and Patient-derived Xenograft Mouse Model Study American Journal of Obstetrics and Gynecology. Aug, 2015 | Pubmed ID: 25840272 Posttranslational Modification of Sirt6 Activity by Peroxynitrite Free Radical Biology & Medicine. Feb, 2015 | Pubmed ID: 25476852 Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by CAMP 1 Reduce Pancreatic Cancer Metastasis in Vivo Molecular Pharmacology. Feb, 2015 | Pubmed ID: 25385424 Nicotine Accelerates Diabetes-induced Retinal Changes Current Eye Research. Apr, 2015 | Pubmed ID: 24911405 TWEAK/Fn14 Pathway is a Novel Mediator of Retinal Neovascularization Investigative Ophthalmology & Visual Science. Feb, 2014 | Pubmed ID: 24408972 Monitoring Therapeutic Treatments Against Infections Using Imaging Techniques Pathogens (Basel, Switzerland). Jun, 2013 | Pubmed ID: 24349761 Image-based Noninvasive Evaluation of Colorectal Mucosal Injury in Sheep After Topical Application of Microbicides Sexually Transmitted Diseases. Nov, 2013 | Pubmed ID: 24113407 Interleukin-27 Gene Delivery for Modifying Malignant Interactions Between Prostate Tumor and Bone Human Gene Therapy. Dec, 2013 | Pubmed ID: 24028178 Pharmacokinetics of a Multipurpose Pod-intravaginal Ring Simultaneously Delivering Five Drugs in an Ovine Model Antimicrobial Agents and Chemotherapy. Aug, 2013 | Pubmed ID: 23752507 High-resolution Multimodal Imaging of Multiple Evanescent White Dot Syndrome Ophthalmic Surgery, Lasers & Imaging Retina. May-Jun, 2013 | Pubmed ID: 23676237 Heterogeneity in Subcutaneous Adipose Tissue Morphology and Metabolic Complications in Overweight and Obese Women Metabolic Syndrome and Related Disorders. Aug, 2013 | Pubmed ID: 23621112 Optical Coherence Tomography for Assessment of Microbicide Safety in a Small Animal Model Journal of Biomedical Optics. Apr, 2013 | Pubmed ID: 23588808 Nanomedicine for Uterine Leiomyoma Therapy Therapeutic Delivery. Feb, 2013 | Pubmed ID: 23343157 Monitoring Vaginal Epithelial Thickness Changes Noninvasively in Sheep Using Optical Coherence Tomography American Journal of Obstetrics and Gynecology. Apr, 2013 | Pubmed ID: 23333551 Pioglitazone Therapy in Mouse Offspring Exposed to Maternal Obesity American Journal of Obstetrics and Gynecology. Apr, 2013 | Pubmed ID: 23313309 Enhanced Leptin Sensitivity, Reduced Adiposity, and Improved Glucose Homeostasis in Mice Lacking Exchange Protein Directly Activated by Cyclic AMP Isoform 1 Molecular and Cellular Biology. Mar, 2013 | Pubmed ID: 23263987 Retinal Optical Coherence Tomography Image Enhancement Via Shrinkage Denoising Using Double-density Dual-tree Complex Wavelet Transform Journal of Biomedical Optics. Nov, 2012 | Pubmed ID: 23117804 Automated Segmentation Algorithm for Detection of Changes in Vaginal Epithelial Morphology Using Optical Coherence Tomography Journal of Biomedical Optics. Nov, 2012 | Pubmed ID: 23117799 Nicotine Exposure Exacerbates Development of Cataracts in a Type 1 Diabetic Rat Model Experimental Diabetes Research. 2012 | Pubmed ID: 23049540 In Vivo Imaging of Photoreceptor Disruption Associated with Age-related Macular Degeneration: A Pilot Study Lasers in Surgery and Medicine. Oct, 2012 | Pubmed ID: 22930575 Quantitative Assessment of Microbicide-induced Injury in the Ovine Vaginal Epithelium Using Confocal Microendoscopy BMC Infectious Diseases. Feb, 2012 | Pubmed ID: 22375797 Tenofovir and Tenofovir Disoproxil Fumarate Pharmacokinetics from Intravaginal Rings AIDS (London, England). Mar, 2012 | Pubmed ID: 22210639 Simultaneous Delivery of Tenofovir and Acyclovir Via an Intravaginal Ring Antimicrobial Agents and Chemotherapy. Feb, 2012 | Pubmed ID: 22123689 Optical Coherence Tomography Compared with Colposcopy for Assessment of Vaginal Epithelial Damage: a Randomized Controlled Trial Obstetrics and Gynecology. Dec, 2011 | Pubmed ID: 22105265 Quantitative Evaluation of Retinal Response to Laser Photocoagulation Using Dual-wavelength Fundus Autofluorescence Imaging in a Small Animal Model Investigative Ophthalmology & Visual Science. Aug, 2011 | Pubmed ID: 21715352 Benzalkonium Chloride Causes Colposcopic Changes and Increased Susceptibility to Genital Herpes Infection in Mice Sexually Transmitted Diseases. Sep, 2010 | Pubmed ID: 20803781 Estradiol Improves Genital Herpes Vaccine Efficacy in Mice Vaccine. Sep, 2009 | Pubmed ID: 19660586 Use of High-resolution Confocal Imaging of the Vaginal Epithelial Microstructure to Detect Microbicide Toxicity The Journal of Infectious Diseases. May, 2009 | Pubmed ID: 19355817 High Resolution Imaging of Epithelial Injury in the Sheep Cervicovaginal Tract: a Promising Model for Testing Safety of Candidate Microbicides Sexually Transmitted Diseases. May, 2009 | Pubmed ID: 19295469 Engineering of Hetero-functional Gold Nanorods for the in Vivo Molecular Targeting of Breast Cancer Cells Nano Letters. Jan, 2009 | Pubmed ID: 19072129 Cardiac Preconditioning with Local Laser-induced Hyperthermia The Journal of Surgical Research. Oct, 2008 | Pubmed ID: 18657832 Application of Optical Coherence Tomography for Monitoring Changes in Cervicovaginal Epithelial Morphology in Macaques: Potential for Assessment of Microbicide Safety Sexually Transmitted Diseases. Mar, 2008 | Pubmed ID: 18091028 High Sensitivity of in Vivo Detection of Gold Nanorods Using a Laser Optoacoustic Imaging System Nano Letters. Jul, 2007 | Pubmed ID: 17570730 Topical Imiquimod As an Adjuvant to Laser Removal of Mature Tattoos in an Animal Model Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]. Mar, 2007 | Pubmed ID: 17338690 Nanoscale Engineering of a Cellular Interface with Semiconductor Nanoparticle Films for Photoelectric Stimulation of Neurons Nano Letters. Feb, 2007 | Pubmed ID: 17298018 Whole-body Hyperthermia Induces Up-regulation of Vascular Endothelial Growth Factor Accompanied by Neovascularization in Cardiac Tissue Life Sciences. Oct, 2006 | Pubmed ID: 16979666 Optoacoustic, Noninvasive, Real-time, Continuous Monitoring of Cerebral Blood Oxygenation: an in Vivo Study in Sheep Anesthesiology. Jan, 2005 | Pubmed ID: 15618789 Bioconjugated Gold Nanoparticles As a Molecular Based Contrast Agent: Implications for Imaging of Deep Tumors Using Optoacoustic Tomography Molecular Imaging and Biology. Sep-Oct, 2004 | Pubmed ID: 15380744 Monitoring of Rabbit Cornea Response to Dehydration Stress by Optical Coherence Tomography Investigative Ophthalmology & Visual Science. Aug, 2004 | Pubmed ID: 15277477 Phase-sensitive Optical Low-coherence Reflectometry for the Detection of Analyte Concentrations Applied Optics. Jun, 2004 | Pubmed ID: 15219020 Unique Temperature-activated Neurons from Pit Viper Thermosensors American Journal of Physiology. Cell Physiology. Nov, 2004 | Pubmed ID: 15213055 Simvastatin-induced Myocardial Protection Against Ischemia-reperfusion Injury is Mediated by Activation of ATP-sensitive K+ Channels Coronary Artery Disease. Feb, 2004 | Pubmed ID: 15201621 Reduction of Infarct Size by Short-term Pretreatment with Atorvastatin Cardiovascular Drugs and Therapy. Jan, 2003 | Pubmed ID: 12843684 Specificity of Noninvasive Blood Glucose Sensing Using Optical Coherence Tomography Technique: a Pilot Study Physics in Medicine and Biology. May, 2003 | Pubmed ID: 12812453 Precision of Measurement of Tissue Optical Properties with Optical Coherence Tomography Applied Optics. Jun, 2003 | Pubmed ID: 12790454 Wide-band Spectral Tuning of Heat Receptors in the Pit Organ of the Copperhead Snake (Crotalinae) American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Feb, 2003 | Pubmed ID: 12561787 Noninvasive Blood Glucose Monitoring with Optical Coherence Tomography: a Pilot Study in Human Subjects Diabetes Care. Dec, 2002 | Pubmed ID: 12453971 Optoacoustic Technique for Noninvasive Monitoring of Blood Oxygenation: a Feasibility Study Applied Optics. Aug, 2002 | Pubmed ID: 12153109 Microsurgical Dissection and Tissue Clearing for High Resolution Intact Whole Retina and Vitreous Imaging Hossein Nazari1,2, Maxim Ivannikov2, Lorenzo Ochoa2,3, Gracie Vargas2,3, Massoud Motamedi3,4 1Department of Ophthalmology and Visual Neuroscience, University of Minnesota, 2Department of Neuroscience, Cell Biology, and Anatomy, University of Texas Medical Branch, 3Biomedical Engineering and Imaging Sciences Group, University of Texas Medical Branch, 4Department of Ophthalmology, University of Texas Medical Branch JoVE 61595 Neuroscience
Microsurgical Dissection and Tissue Clearing for High Resolution Intact Whole Retina and Vitreous Imaging Hossein Nazari1,2, Maxim Ivannikov2, Lorenzo Ochoa2,3, Gracie Vargas2,3, Massoud Motamedi3,4 1Department of Ophthalmology and Visual Neuroscience, University of Minnesota, 2Department of Neuroscience, Cell Biology, and Anatomy, University of Texas Medical Branch, 3Biomedical Engineering and Imaging Sciences Group, University of Texas Medical Branch, 4Department of Ophthalmology, University of Texas Medical Branch JoVE 61595 Neuroscience