Ramani Ramchandran

Publications

• Ciliogenesis Mechanisms Mediated by PAK2-ARL13B Signaling in Brain Endothelial Cells is Responsible for Vascular Stability
  Biochemical Pharmacology. 08, 2022  |   Pubmed ID: 35700757
• Coagulation Factor IIIa () Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype
  Frontiers in Cell and Developmental Biology. 2022  |   Pubmed ID: 35386206
• Cilia Proteins Are Biomarkers of Altered Flow in the Vasculature
  JCI Insight. 03, 2022  |   Pubmed ID: 35143420
• Editorial: Molecular Mechanisms and Signaling in Endothelial Cell Biology and Vascular Heterogeneity
  Frontiers in Cell and Developmental Biology. 2021  |   Pubmed ID: 34977049
• RNA-binding Protein FXR1 Drives CMYC Translation by Recruiting EIF4F Complex to the Translation Start Site
  Cell Reports. 11, 2021  |   Pubmed ID: 34731628
• The Yin and the Yang of Transformative Research During the COVID-19 Pandemic-A Perspective
  Frontiers in Pediatrics. 2021  |   Pubmed ID: 34249804
• SVEGFR1 Is Enriched in Hepatic Vein Blood-Evidence for a Provisional Hepatic Factor Candidate?
  Frontiers in Pediatrics. 2021  |   Pubmed ID: 34195162
• Established, New and Emerging Concepts in Brain Vascular Development
  Frontiers in Physiology. 2021  |   Pubmed ID: 33643074
• DUSP5 Expression in Left Ventricular Cardiomyocytes of Young Hearts Regulates Thyroid Hormone (T3)-induced Proliferative ERK1/2 Signaling
  Scientific Reports. 12, 2020  |   Pubmed ID: 33318551
• Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling
  Cancer Research. 12, 2020  |   Pubmed ID: 33087324
• SNRK: a Metabolic Regulator with Multifaceted Role in Development and Disease
  Vessel Plus. 2020  |   Pubmed ID: 32968716
• Cystathione β-synthase Regulates HIF-1α Stability Through Persulfidation of PHD2
  Science Advances. 07, 2020  |   Pubmed ID: 32937467
• Astrocytes Influence Medulloblastoma Phenotypes and CD133 Surface Expression
  PloS One. 2020  |   Pubmed ID: 32628717
• Rapamycin Treatment Correlates Changes in Primary Cilia Expression with Cell Cycle Regulation in Epithelial Cells
  Biochemical Pharmacology. 08, 2020  |   Pubmed ID: 32470549
• Hepatic Vein Blood Increases Lung Microvascular Angiogenesis and Endothelial Cell Survival-Toward an Understanding of Univentricular Circulation
  Seminars in Thoracic and Cardiovascular Surgery. Winter, 2020  |   Pubmed ID: 32387780
• ERBB3-induced Furin Promotes the Progression and Metastasis of Ovarian Cancer Via the IGF1R/STAT3 Signaling Axis
  Oncogene. 04, 2020  |   Pubmed ID: 32029900
• MiRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer
  Cell Reports. 12, 2019  |   Pubmed ID: 31875548
• Discovery and Characterization of Halogenated Xanthene Inhibitors of DUSP5 As Potential Photodynamic Therapeutics
  Journal of Photochemistry and Photobiology. A, Chemistry. Apr, 2019  |   Pubmed ID: 31839699
• Cardiomyocyte-Specific Prevents Inflammation in the Heart
  Journal of the American Heart Association. 11, 2019  |   Pubmed ID: 31718444
• Interaction of Tumor Cells and Astrocytes Promotes Breast Cancer Brain Metastases Through TGF-β2/ANGPTL4 Axes
  NPJ Precision Oncology. 2019  |   Pubmed ID: 31602400
• Lessons Learned from a LncRNA Odyssey for Two Genes with Vascular Functions, DLL4 and TIE1
  Vascular Pharmacology. 03, 2019  |   Pubmed ID: 30910126
• Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish ( Danio Rerio)
  Arteriosclerosis, Thrombosis, and Vascular Biology. 12, 2018  |   Pubmed ID: 30571172
• Corrigendum: Cystathionine β-Synthase Is Necessary for Axis Development
  Frontiers in Cell and Developmental Biology. 2018  |   Pubmed ID: 30310813
• Temporal and Spatial Post-Transcriptional Regulation of Zebrafish MRNA by Long Noncoding RNA During Brain Vascular Assembly
  Arteriosclerosis, Thrombosis, and Vascular Biology. 07, 2018  |   Pubmed ID: 29724820
• Cystathionine β-Synthase Is Necessary for Axis Development
  Frontiers in Cell and Developmental Biology. 2018  |   Pubmed ID: 29503817
• SNRK (Sucrose Nonfermenting 1-Related Kinase) Promotes Angiogenesis In Vivo
  Arteriosclerosis, Thrombosis, and Vascular Biology. 02, 2018  |   Pubmed ID: 29242271
• Sucrose Non-Fermenting Related Kinase Expression in Ovarian Cancer and Correlation with Clinical Features
  Cancer Investigation. Aug, 2017  |   Pubmed ID: 28722495
• MiRNA-Mediated RNA Activation in Mammalian Cells
  Advances in Experimental Medicine and Biology. 2017  |   Pubmed ID: 28639193
• Serendipitous Discovery of Light-induced (In Situ) Formation of an Azo-bridged Dimeric Sulfonated Naphthol As a Potent PTP1B Inhibitor
  BMC Biochemistry. 05, 2017  |   Pubmed ID: 28569147
• Dual Specificity Phosphatase 5 Is Essential for T Cell Survival
  PloS One. 2016  |   Pubmed ID: 27936095
• Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function
  Circulation. Cardiovascular Genetics. Dec, 2016  |   Pubmed ID: 27780848
• Critical Role of the Secondary Binding Pocket in Modulating the Enzymatic Activity of DUSP5 Toward Phosphorylated ERKs
  Biochemistry. Nov, 2016  |   Pubmed ID: 27739308
• E-cadherin Re-expression Shows in Vivo Evidence for Mesenchymal to Epithelial Transition in Clonal Metastatic Breast Tumor Cells
  Oncotarget. Jul, 2016  |   Pubmed ID: 27270319
• The LncRNA PVT1 Contributes to the Cervical Cancer Phenotype and Associates with Poor Patient Prognosis
  PloS One. 2016  |   Pubmed ID: 27232880
• Nogo-B Receptor Deficiency Causes Cerebral Vasculature Defects During Embryonic Development in Mice
  Developmental Biology. Feb, 2016  |   Pubmed ID: 26746789
• Cystathionine β-synthase Regulates Endothelial Function Via Protein S-sulfhydration
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2016  |   Pubmed ID: 26405298
• Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR) Regulates Lipolysis in White Adipocytes Via the PTEN/AKT Signaling Pathway
  PloS One. 2015  |   Pubmed ID: 26692198
• Identification of Inhibitors That Target Dual-specificity Phosphatase 5 Provide New Insights into the Binding Requirements for the Two Phosphate Pockets
  BMC Biochemistry. Aug, 2015  |   Pubmed ID: 26286528
• Gene Expression in Experimental Aortic Coarctation and Repair: Candidate Genes for Therapeutic Intervention?
  PloS One. 2015  |   Pubmed ID: 26207811
• RhoC Maintains Vascular Homeostasis by Regulating VEGF-induced Signaling in Endothelial Cells
  Journal of Cell Science. 10, 2015  |   Pubmed ID: 26136364
• SIGIRR Genetic Variants in Premature Infants with Necrotizing Enterocolitis
  Pediatrics. Jun, 2015  |   Pubmed ID: 25963006
• Delta-like 4 MRNA is Regulated by Adjacent Natural Antisense Transcripts
  Vascular Cell. 2015  |   Pubmed ID: 25914805
• Lipopolysaccharide (LPS)-mediated Angiopoietin-2-dependent Autocrine Angiogenesis is Regulated by NADPH Oxidase 2 (Nox2) in Human Pulmonary Microvascular Endothelial Cells
  The Journal of Biological Chemistry. Feb, 2015  |   Pubmed ID: 25568324
• Organization for Rare Diseases India (ORDI) - Addressing the Challenges and Opportunities for the Indian Rare Diseases' Community
  Genetics Research. Aug, 2014  |   Pubmed ID: 25579084
• Protein Expression, Characterization and Activity Comparisons of Wild Type and Mutant DUSP5 Proteins
  BMC Biochemistry. Dec, 2014  |   Pubmed ID: 25519881
• Sucrose Non-fermenting Related Kinase Enzyme is Essential for Cardiac Metabolism
  Biology Open. Dec, 2014  |   Pubmed ID: 25505152
• Transcriptional Inhibition of Etv2 Expression is Essential for Embryonic Cardiac Development
  Developmental Biology. Sep, 2014  |   Pubmed ID: 24984259
• SIRT2 Regulates Ciliogenesis and Contributes to Abnormal Centrosome Amplification Caused by Loss of Polycystin-1
  Human Molecular Genetics. Mar, 2014  |   Pubmed ID: 24203696
• Astrocytes Directly Influence Tumor Cell Invasion and Metastasis in Vivo
  PloS One. 2013  |   Pubmed ID: 24324647
• Mmp17b is Essential for Proper Neural Crest Cell Migration in Vivo
  PloS One. 2013  |   Pubmed ID: 24098510
• Protein Structure in Context: the Molecular Landscape of Angiogenesis
  Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. Jul-Aug, 2013  |   Pubmed ID: 23868376
• Endothelial Cell-specific Chemotaxis Receptor (ECSCR) Enhances Vascular Endothelial Growth Factor (VEGF) Receptor-2/kinase Insert Domain Receptor (KDR) Activation and Promotes Proteolysis of Internalized KDR
  The Journal of Biological Chemistry. Apr, 2013  |   Pubmed ID: 23393131
• Role of Dual-specificity Protein Phosphatase-5 in Modulating the Myogenic Response in Rat Cerebral Arteries
  Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2013  |   Pubmed ID: 23172031
• Studies on Axenfeld-Rieger Syndrome Patients and Mice Reveal Foxc1's Role in Corneal Neovascularization
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012  |   Pubmed ID: 22308435
• Reactive Oxygen Species Driven Angiogenesis by Inorganic Nanorods
  Nano Letters. Nov, 2011  |   Pubmed ID: 21967244
• Sox Factors Transcriptionally Regulate ROBO4 Gene Expression in Developing Vasculature in Zebrafish
  The Journal of Biological Chemistry. Sep, 2011  |   Pubmed ID: 21730073
• Rap1 Promotes VEGFR2 Activation and Angiogenesis by a Mechanism Involving Integrin αvβ₃
  Blood. Aug, 2011  |   Pubmed ID: 21636859
• Fli+ Etsrp+ Hemato-vascular Progenitor Cells Proliferate at the Lateral Plate Mesoderm During Vasculogenesis in Zebrafish
  PloS One. Feb, 2011  |   Pubmed ID: 21364913
• Natural Antisense Transcript: a Concomitant Engagement with Protein-coding Transcript
  Oncotarget. Oct, 2010  |   Pubmed ID: 21311100
• Nogo-B Receptor is Essential for Angiogenesis in Zebrafish Via Akt Pathway
  Blood. Dec, 2010  |   Pubmed ID: 20813898
• Endothelial Cell-specific Chemotaxis Receptor (ecscr) Promotes Angioblast Migration During Vasculogenesis and Enhances VEGF Receptor Sensitivity
  Blood. Jun, 2010  |   Pubmed ID: 20086248
• A Noncoding Antisense RNA in Tie-1 Locus Regulates Tie-1 Function in Vivo
  Blood. Jan, 2010  |   Pubmed ID: 19880500
• Thiolutin Inhibits Endothelial Cell Adhesion by Perturbing Hsp27 Interactions with Components of the Actin and Intermediate Filament Cytoskeleton
  Cell Stress & Chaperones. Mar, 2010  |   Pubmed ID: 19579057
• Specific Inhibition of Cyclin-dependent Kinase 5 Activity Induces Motor Neuron Development in Vivo
  Biochemical and Biophysical Research Communications. Aug, 2009  |   Pubmed ID: 19523926
• Dusp-5 and Snrk-1 Coordinately Function During Vascular Development and Disease
  Blood. Jan, 2009  |   Pubmed ID: 18927432
• Snrk-1 is Involved in Multiple Steps of Angioblast Development and Acts Via Notch Signaling Pathway in Artery-vein Specification in Vertebrates
  Blood. Jan, 2009  |   Pubmed ID: 18723694
• A Whole-animal Microplate Assay for Metabolic Rate Using Zebrafish
  Journal of Biomolecular Screening. Dec, 2008  |   Pubmed ID: 19029015
• Silencing of Directional Migration in Roundabout4 Knockdown Endothelial Cells
  BMC Cell Biology. Nov, 2008  |   Pubmed ID: 18980679
• Syx, a RhoA Guanine Exchange Factor, is Essential for Angiogenesis in Vivo
  Circulation Research. Sep, 2008  |   Pubmed ID: 18757825
• Expression Pattern for Unc5b, an Axon Guidance Gene in Embryonic Zebrafish Development
  Gene Expression. 2007  |   Pubmed ID: 17708418