Weston B. Struwe

Publications

• Measuring Protein-Protein Interactions and Quantifying Their Dissociation Constants with Mass Photometry
  Current Protocols. Jan, 2024  |   Pubmed ID: 38224147
• Uncovering the Role of -Glycan Occupancy on the Cooperative Assembly of Spike and Angiotensin Converting Enzyme 2 Complexes: Insights from Glycoengineering and Native Mass Spectrometry
  Journal of the American Chemical Society. Apr, 2023  |   Pubmed ID: 37000485
• Engineer RNA-Protein Nanowires As Light-Responsive Biomaterials
  Small (Weinheim an Der Bergstrasse, Germany). Mar, 2023  |   Pubmed ID: 36642821
• Mass Photometry Reveals SARS-CoV-2 Spike Stabilisation to Impede ACE2 Binding Through Altered Conformational Dynamics
  Chemical Communications (Cambridge, England). Nov, 2022  |   Pubmed ID: 36317551
• An N-glycan on the C2 Domain of JAGGED1 is Important for Notch Activation
  Science Signaling. Oct, 2022  |   Pubmed ID: 36219682
• Direct Observation of the Molecular Mechanism Underlying Protein Polymerization
  Science Advances. Sep, 2022  |   Pubmed ID: 36044567
• State-of-the-art Glycosaminoglycan Characterization
  Mass Spectrometry Reviews. Nov, 2022  |   Pubmed ID: 34608657
• Formation and Fragmentation of Doubly and Triply Charged Ions in the Negative Ion Spectra of Neutral N-glycans from Viral and Other Glycoproteins
  Analytical and Bioanalytical Chemistry. Dec, 2021  |   Pubmed ID: 34342671
• Label-free Methods for Optical Characterization of Protein-protein Interactions
  Physical Chemistry Chemical Physics : PCCP. Aug, 2021  |   Pubmed ID: 34342317
• Identification of N-glycans with GalNAc-containing Antennae from Recombinant HIV Trimers by Ion Mobility and Negative Ion Fragmentation
  Analytical and Bioanalytical Chemistry. Dec, 2021  |   Pubmed ID: 34327564
• Native Mass Spectrometry Meets Glycomics: Resolving Structural Detail and Occupancy of Glycans on Intact Glycoproteins
  Analytical Chemistry. Aug, 2021  |   Pubmed ID: 34279906
• Assessing Antigen Structural Integrity Through Glycosylation Analysis of the SARS-CoV-2 Viral Spike
  ACS Central Science. Apr, 2021  |   Pubmed ID: 34056088
• Mass Photometry of Membrane Proteins
  Chem. Jan, 2021  |   Pubmed ID: 33511302
• Hyper-truncated Asn355- and Asn391-glycans Modulate the Activity of Neutrophil Granule Myeloperoxidase
  The Journal of Biological Chemistry. 2021  |   Pubmed ID: 33273015
• Correlating Glycoforms of DC-SIGN with Stability Using a Combination of Enzymatic Digestion and Ion Mobility Mass Spectrometry
  Angewandte Chemie (International Ed. in English). Sep, 2020  |   Pubmed ID: 33462887
• Single Molecule Mass Photometry of Nucleic Acids
  Nucleic Acids Research. Sep, 2020  |   Pubmed ID: 32756898
• Quantifying the Heterogeneity of Macromolecular Machines by Mass Photometry
  Nature Communications. Apr, 2020  |   Pubmed ID: 32286308
• Shotgun Ion Mobility Mass Spectrometry Sequencing of Heparan Sulfate Saccharides
  Nature Communications. Mar, 2020  |   Pubmed ID: 32198425
• Quantifying Protein-Protein Interactions by Molecular Counting with Mass Photometry
  Angewandte Chemie (International Ed. in English). Jun, 2020  |   Pubmed ID: 32167227
• A Bipartite Structural Organization Defines the SERINC Family of HIV-1 Restriction Factors
  Nature Structural & Molecular Biology. Jan, 2020  |   Pubmed ID: 31907454
• Ion Mobility-Mass Spectrometry of Glycoconjugates
  Methods in Molecular Biology (Clifton, N.J.). 2020  |   Pubmed ID: 31729663
• Separation of Isomeric Glycans by Ion Mobility Spectrometry - the Impact of Fluorescent Labelling
  The Analyst. Sep, 2019  |   Pubmed ID: 31380551
• Towards a Standardized Bioinformatics Infrastructure for N- and O-glycomics
  Nature Communications. 07, 2019  |   Pubmed ID: 31332201
• Relating Glycoprotein Structural Heterogeneity to Function - Insights from Native Mass Spectrometry
  Current Opinion in Structural Biology. Oct, 2019  |   Pubmed ID: 31326232
• Separation of Isomeric Glycans by Ion Mobility and Liquid Chromatography-Mass Spectrometry
  Analytical Chemistry. Aug, 2019  |   Pubmed ID: 31298840
• Probing -glycoprotein Microheterogeneity by Lectin Affinity Purification-mass Spectrometry Analysis
  Chemical Science. May, 2019  |   Pubmed ID: 31183067
• In-depth Structural Analysis of Glycans in the Gas Phase
  Chemical Science. Feb, 2019  |   Pubmed ID: 30809341
• The Minimum Information Required for a Glycomics Experiment (MIRAGE) Project: LC Guidelines
  Glycobiology. May, 2019  |   Pubmed ID: 30778580
• A Mass-Spectrometry-Based Modelling Workflow for Accurate Prediction of IgG Antibody Conformations in the Gas Phase
  Angewandte Chemie (International Ed. in English). Dec, 2018  |   Pubmed ID: 30408305
• Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen
  Cell Reports. Aug, 2018  |   Pubmed ID: 30134158
• N-glycan Microheterogeneity Regulates Interactions of Plasma Proteins
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2018  |   Pubmed ID: 30111543
• Publisher Correction: The Jumonji-C Oxygenase JMJD7 Catalyzes (3S)-lysyl Hydroxylation of TRAFAC GTPases
  Nature Chemical Biology. Oct, 2018  |   Pubmed ID: 29950663
• The Jumonji-C Oxygenase JMJD7 Catalyzes (3S)-lysyl Hydroxylation of TRAFAC GTPases
  Nature Chemical Biology. Jul, 2018  |   Pubmed ID: 29915238
• Structural Insights into the Broad-Spectrum Antiviral Target Endoplasmic Reticulum Alpha-Glucosidase II
  Advances in Experimental Medicine and Biology. 2018  |   Pubmed ID: 29845539
• Structural Studies of Fucosylated N-Glycans by Ion Mobility Mass Spectrometry and Collision-Induced Fragmentation of Negative Ions
  Journal of the American Society for Mass Spectrometry. Jun, 2018  |   Pubmed ID: 29790113
• Signature of Antibody Domain Exchange by Native Mass Spectrometry and Collision-Induced Unfolding
  Analytical Chemistry. Jun, 2018  |   Pubmed ID: 29757629
• Quantitative Mass Imaging of Single Biological Macromolecules
  Science (New York, N.Y.). Apr, 2018  |   Pubmed ID: 29700264
• Fucose Migration in Intact Protonated Glycan Ions: A Universal Phenomenon in Mass Spectrometry
  Angewandte Chemie (International Ed. in English). Jun, 2018  |   Pubmed ID: 29688603
• Collision Cross Sections and Ion Mobility Separation of Fragment Ions from Complex N-Glycans
  Journal of the American Society for Mass Spectrometry. Jun, 2018  |   Pubmed ID: 29675741
• Isomer Information from Ion Mobility Separation of High-Mannose Glycan Fragments
  Journal of the American Society for Mass Spectrometry. May, 2018  |   Pubmed ID: 29508223
• Structural Principles That Enable Oligomeric Small Heat-shock Protein Paralogs to Evolve Distinct Functions
  Science (New York, N.Y.). Feb, 2018  |   Pubmed ID: 29472485
• Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages
  Journal of Proteome Research. Mar, 2018  |   Pubmed ID: 29420040
• Glycosylation Profiling to Evaluate Glycoprotein Immunogens Against HIV-1
  Expert Review of Proteomics. Oct, 2017  |   Pubmed ID: 28870097
• Convergent Immunological Solutions to Argentine Hemorrhagic Fever Virus Neutralization
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2017  |   Pubmed ID: 28630325
• Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers
  Journal of Virology. Aug, 2017  |   Pubmed ID: 28539451
• Glycan Fingerprinting Via Cold-Ion Infrared Spectroscopy
  Angewandte Chemie (International Ed. in English). Sep, 2017  |   Pubmed ID: 28513924
• The Tetrameric Plant Lectin BanLec Neutralizes HIV Through Bidentate Binding to Specific Viral Glycans
  Structure (London, England : 1993). May, 2017  |   Pubmed ID: 28434916
• Identification of Lewis and Blood Group Carbohydrate Epitopes by Ion Mobility-Tandem-Mass Spectrometry Fingerprinting
  Analytical Chemistry. Feb, 2017  |   Pubmed ID: 28192913
• The Role of Interfacial Lipids in Stabilizing Membrane Protein Oligomers
  Nature. Jan, 2017  |   Pubmed ID: 28077870
• The Minimum Information Required for a Glycomics Experiment (MIRAGE) Project: Improving the Standards for Reporting Glycan Microarray-based Data
  Glycobiology. 04, 2017  |   Pubmed ID: 27993942
• Global N-Glycan Site Occupancy of HIV-1 Gp120 by Metabolic Engineering and High-Resolution Intact Mass Spectrometry
  ACS Chemical Biology. Feb, 2017  |   Pubmed ID: 27984693
• Molecular Architecture of the Cleavage-Dependent Mannose Patch on a Soluble HIV-1 Envelope Glycoprotein Trimer
  Journal of Virology. Jan, 2017  |   Pubmed ID: 27807235
• Ion Mobility Separation of Deprotonated Oligosaccharide Isomers - Evidence for Gas-phase Charge Migration
  Chemical Communications (Cambridge, England). Oct, 2016  |   Pubmed ID: 27711324
• The Minimum Information Required for a Glycomics Experiment (MIRAGE) Project: Sample Preparation Guidelines for Reliable Reporting of Glycomics Datasets
  Glycobiology. 09, 2016  |   Pubmed ID: 27654115
• Antibody Production Using a Ciliate Generates Unusual Antibody Glycoforms Displaying Enhanced Cell-killing Activity
  MAbs. 2016  |   Pubmed ID: 27594301
• Optimal Synthetic Glycosylation of a Therapeutic Antibody
  Angewandte Chemie (Weinheim an Der Bergstrasse, Germany). Feb, 2016  |   Pubmed ID: 27546920
• Travelling-wave Ion Mobility Mass Spectrometry and Negative Ion Fragmentation of Hybrid and Complex N-glycans
  Journal of Mass Spectrometry : JMS. Nov, 2016  |   Pubmed ID: 27477117
• Structures of Mammalian ER α-glucosidase II Capture the Binding Modes of Broad-spectrum Iminosugar Antivirals
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2016  |   Pubmed ID: 27462106
• Immune Recruitment or Suppression by Glycan Engineering of Endogenous and Therapeutic Antibodies
  Biochimica Et Biophysica Acta. Aug, 2016  |   Pubmed ID: 27105835
• Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein
  Cell Reports. Mar, 2016  |   Pubmed ID: 26972002
• Travelling-wave Ion Mobility and Negative Ion Fragmentation of High-mannose N-glycans
  Journal of Mass Spectrometry : JMS. Mar, 2016  |   Pubmed ID: 26956389
• High-resolution Mass Spectrometry of Small Molecules Bound to Membrane Proteins
  Nature Methods. Apr, 2016  |   Pubmed ID: 26901650
• Optimal Synthetic Glycosylation of a Therapeutic Antibody
  Angewandte Chemie (International Ed. in English). Feb, 2016  |   Pubmed ID: 26756880
• Structural Characterization and Biological Implications of Sulfated N-glycans in a Serine Protease from the Neotropical Moth Hylesia Metabus (Cramer [1775]) (Lepidoptera: Saturniidae)
  Glycobiology. Mar, 2016  |   Pubmed ID: 26537504
• GlycoMob: an Ion Mobility-mass Spectrometry Collision Cross Section Database for Glycomics
  Glycoconjugate Journal. Jun, 2016  |   Pubmed ID: 26314736
• Studying the Active-site Loop Movement of the São Paolo Metallo-β-lactamase-1†Electronic Supplementary Information (ESI) Available: Procedures for Protein Expression and Purification, F-labelling, Crystallisation, Data Collection, and Structure Determination, Table of Crystallographic Data, Table of Crystallographic Parameters and Refinement Statistics, Figures Showing Binding Mode and Distances, Procedures for Mass Spectrometry Measurements, Differential Scanning Fluorimetry Measurements, Stopped-flow Measurements and Other Kinetics Measurements. See DOI: 10.1039/c4sc01752hClick Here for Additional Data File
  Chemical Science. Feb, 2015  |   Pubmed ID: 25717359
• Native Mass Spectrometry: Towards High-throughput Structural Proteomics
  Methods in Molecular Biology (Clifton, N.J.). 2015  |   Pubmed ID: 25502208
• Ejection of Structural Zinc Leads to Inhibition of γ-butyrobetaine Hydroxylase
  Bioorganic & Medicinal Chemistry Letters. Nov, 2014  |   Pubmed ID: 25266780
• MIRAGE: the Minimum Information Required for a Glycomics Experiment
  Glycobiology. May, 2014  |   Pubmed ID: 24653214
• Increase in Sialylation and Branching in the Mouse Serum N-glycome Correlates with Inflammation and Ovarian Tumour Progression
  PloS One. 2013  |   Pubmed ID: 24023608
• The Minimum Information Required for a Glycomics Experiment (MIRAGE) Project: Improving the Standards for Reporting Mass-spectrometry-based Glycoanalytic Data
  Molecular & Cellular Proteomics : MCP. Apr, 2013  |   Pubmed ID: 23378518