Jennifer Hoover, chief scientist of the Infectious Disease Therapy Area Unit at GlaxoSmithKline, published in JoVE to reduce animal usage and save training time – more than two months in each instance – involved in teaching an innovative pneumonia model.
Challenge: Mrs. Hoover’s lab optimized, validated, and perfected a pneumonia model that industry researchers, contract research organizations, and academic labs have sought to learn over the years. Before publishing with JoVE the only way to teach the detailed model to other researchers was to host them on site; site visits required substantial coordination and paperwork for all parties involved.
Solution: In response to the demand from industry researchers to learn from her lab, Mrs. Hoover sought a format that could illustrate the technical details of the model, and easily transfer this technique to other interested labs around the world. JoVE achieved both of these goals.
She published “A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii” in JoVE Video Journal in January 2017.
Results/Benefits:
- As a result of her publication, Mrs. Hoover saves time by sharing the JoVE Video Article to explain the model, instead of hosting visits and completing all the paperwork involved. This saves her at least two months for every training request, she said.
- With the publication, she has been able to honor GSK’s mission in reducing the number of animals required for learning and practicing a new technique.
- Mrs. Hoover used her JoVE video to present at a U.S. FDA Advisory Committee meeting and a workshop sponsored by National Institute of Allergy and Infectious Disease (NIAID).
- The pneumonia model has been viewed in 24 different countries since it was published in January, 2017.
- Overall, Mrs. Hoover summarizes, “By providing explicit “how to” instructions and a video demo, it exemplified GSK’s commitment to the 3 R’s of animal research (reduce, replace and refine).”
If you are a scientist, administrator or librarian looking to save your lab time, money and resources, consider adding JoVE to your organization.
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