Shenyang Agricultural University 2 articles published in JoVE Immunology and Infection A Catheter-Related Candida albicans Infection Model in Mouse Chen Yang1, Fei Mo2, Jiaxue Zhang1, Peipei Zhang1, Qingqing Li1, Jiye Zhang1 1 We establish a mouse model of C.albicans-associated catheter-related infection (CRI), in which biofilm forms on the catheter, and the interaction between C.albicans and host correlates well with the clinical CRI. This model helps screen therapies for C.albicans biofilm-associated CRI, laying a foundation for clinical transformation. Immunology and Infection A Periprosthetic Joint Candida albicans Infection Model in Mouse Chen Yang1, Jiaxue Zhang1, Fei Mo2, Peipei Zhang1, Qingqing Li1, Jiye Zhang1 1 Periprosthetic joint infection (PJI) caused by dangerous pathogens is common in clinical orthopedics. Existing animal models cannot accurately simulate the actual situation of PJI. Here, we established a Candida albicans biofilm-associated PJI mouse model to research and develop new therapeutics for PJI.