JSS Academy of Higher Education and Research 1 article published in JoVE Bioengineering Doxycycline Loaded Collagen-Chitosan Composite Scaffold for the Accelerated Healing of Diabetic Wounds Bharat Kumar Reddy Sanapalli1, Kalaivani Chinna Gounder1, Nilesh Sudhakar Ambhore2, Gowthamarajan Kuppuswamy1, Praveen Thaggikuppe Krishnamurthy3, Veera Venkata Satyanarayana Reddy Karri1 1Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, 2Department of Pharmaceutical Sciences, School of Pharmacy, North Dakota state university, 3Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research The prepared DOX-CL scaffold satisfied the prerequisites of an ideal DW dressing in mechanical strength, porosity, water absorption, degradation rate, sustained release, anti-bacterial, biocompatibility, and anti-inflammatory properties, which are considered to be essential for the recovery of damaged tissue in DWs.