ADInstruments 1 article published in JoVE Medicine Catheterization of the Carotid Artery and Jugular Vein to Perform Hemodynamic Measures, Infusions and Blood Sampling in a Conscious Rat Model Jing Feng1, Yvonne Fitz1, Yan Li1, Melinda Fernandez1, Irene Cortes Puch1, Dong Wang1, Stephanie Pazniokas2, Brandon Bucher3, Xizhong Cui1, Steven B. Solomon1 1Critical Care Medicine Department, Clinical Center, National Institutes of Health, 2Harvard Apparatus, 3ADInstruments Vascular accesses to measure hemodynamics, provide fluids and perform blood sampling are important to any small animal model study. We present a technique for implanting catheters into the carotid artery and the common jugular vein in an anesthetized rat for connecting to a system to perform monitoring, infusions and sampling.