La Princesa University Hospital 1 article published in JoVE Engineering Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis Guadalupe Tirma González-Mateo1,2, Lucía Pascual-Antón1, Pilar Sandoval1, Abelardo Aguilera Peralta3, Manuel López-Cabrera1 1Molecular Biology Research Centre Severo Ochoa, Spanish National Research Council, 2IdiPAZ Research Institute, La Paz University Hospital, 3Princesa Research Institute, La Princesa University Hospital This article shows the method for the surgical placement in mice of an intraperitoneal catheter attached to an access port that is positioned at the back of the animal. Moreover, it explains the procedure for a 5/6 nephrectomy to resemble the uremic state of PD patients.