VA Health Care Center 1 article published in JoVE Medicine Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain Hollis E. Krug1,2, Christopher Dorman2, Nicole Blanshan2, Sandra Frizelle2, Maren Mahowald1,2 1Department of Medicine, University of Minnesota, 2Research Department, VA Health Care Center We have developed an evoked measure of arthritis pain and coupled it with a standardized method for measuring spontaneous pain in different murine models of chemically induced arthritis. These measures are sensitive and reproducible for different types of joint pain.