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Stretching korte sequenties van DNA met Constant Force Axiale optisch pincet

Article DOI: 10.3791/3405-v • 08:48 min • October 13th, 2011
October 13th, 2011 •
1, 2, 2
1LSA Biophysics, University of Michigan, 2LSA Biophysics, Department of Physics, University of Michigan

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Wordt het gebruik van een constante kracht axiaal optische pincetten om de mechanische eigenschappen van korte DNA moleculen te verkennen. Door stretching DNA axiaal, minimaliseren we sterische hindernissen en artefacten die in conventionele laterale manipulatie, waardoor we DNA-moleculen te bestuderen zo kort ~ 100 nm.

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Bioengineering Genetica DNA stretching DNA Axiaal optisch pincet enkel-molecuul biofysica Biofysica
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