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Concentrische Gel Systeem om de biofysische rol van matrix Microenvironment op 3D-Cell Migratie Bestudeer

Article DOI: 10.3791/52735-v • 11:43 min • April 3rd, 2015
April 3rd, 2015 •
1, 2, 2,3
1Systems Biophysics Department, FOM Institute AMOLF, 2Mechanobiology Institute, National University of Singapore, 3Department of Biomedical Engineering, National University of Singapore

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De mechanische eigenschappen en de microstructuur van de extracellulaire matrix sterk beïnvloeden 3D migratie van cellen. Een in vitro werkwijze om de tijdruimtelijk celmigratie gedrag biofysisch variabele omgevingen zowel bevolking en afzonderlijke cel niveaus, gaande beschreven.

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Biotechniek cel migratie collageen biomechanica 3D-celkweek live-cell imaging kanker invasie metastase extracellulaire matrix poriegrootte biopolymeer cytoskelet confocale microscopie
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