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Immunology and Infection

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Udvikling af en hepatitis B virus Reporter system til at overvåge tidlige stadier af Replication Cycle

Article DOI: 10.3791/54849-v • 09:35 min • February 1st, 2017
February 1st, 2017 •
1, 1, 1, 2, 1, 1
1Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, 2Central Pharmaceutical Research Institute, Japan Tobacco Inc.

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Her beskriver vi en nyudviklet hepatitis B virus (HBV) reporter-system til at overvåge de tidlige stadier af HBV livscyklus. Denne forenklede in vitro-system vil støtte i screening af anti-HBV-midler ved anvendelse af en high-throughput strategi.

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Infektion Hepatitis B virus viral vektor Kovalent lukket cirkulær DNA hepatocyt replikationscyklus Ntcp
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