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kwantitatieve 3D

Article DOI: 10.3791/54868-v • 09:33 min • December 26th, 2016
December 26th, 2016 •
1, 1, 1
1Zilkha Neurogenetic Institute, University of Southern California (USC)

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We ontwikkelden een methode voor kwantitatieve 3D in silico modellering (q3DISM) van cerebrale amyloid-β (Aß) fagocytose door mononucleaire fagocyten in diermodellen van de ziekte van Alzheimer. Deze methode kan worden gegeneraliseerd voor de kwantificering van vrijwel elke fagocytische gebeurtenis in vivo.

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Geneeskunde q3DISM TgF344-AD rat APP / PS1 muis cerebrale amyloïdose fagocytose microglia lysosoom fagolysosoom de ziekte van Alzheimer
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