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Phospho flowcytometri med fluorescerende celle stregkodesystem for enkelt celle signalering analyse og biomarkør opdagelse

Article DOI: 10.3791/58386-v • 08:38 min • October 4th, 2018
October 4th, 2018 •
1,2
1Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo, 2K. G. Jebsen Centre for B cell malignancies and K. G. Jebsen Centre for Cancer Immunotherapy, University of Oslo

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Her, præsenteres en protokol til medium-høj overførselshastighed analyse af protein fosforylering begivenheder på cellulært niveau. Phospho flowcytometri er en kraftfuld tilgang til at karakterisere signaling aberrationer, identificere og validere biomarkører og vurdere farmakodynamik.

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Kræftforskning spørgsmål 140 biomarkør celle signalering kronisk lymfatisk leukæmi (CLL) fluorescerende celle stregkodesystem (FCB) Phospho flowcytometri Phospho-proteiner enkelt celle profilering
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