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JoVE Journal Cancer Research
Påvisning av lungetumorprogresjon hos mus ved ultralydavbildning
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Journal (Cancer Research)
Establishing 3-Dimensional Spheroids from Patient-Derived Tumor Samples and Evaluating their Sensitivity to Drugs
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Journal (Cancer Research)
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Påvisning av lungetumorprogresjon hos mus ved ultralydavbildning

Article DOI: 10.3791/60565-v • 04:43 min • February 27th, 2020
February 27th, 2020 •
1,2, 1, 1, 1,3, 1, 1,4
1Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, 2Division of Experimental Medicine, Faculty of Medicine, McGill University, 3Department of Cancer Immunology, Chair of Medical Biotechnology, Poznan University of Medical Sciences, 4Gerald Bronfman Department of Oncology, Faculty of Medicine, McGill University

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Denne protokollen beskriver trinnene som er tatt for å indusere KRAS lungesvulster hos mus, samt kvantifisering av dannede svulster ved ultralydavbildning. Små svulster visualiseres i tidlige tidspunkter som B-linjer. Ved senere tidspunktoppnås relative tumorvolummålinger ved hjelp av måleverktøyet i ultralydprogramvaren.

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Kreftforskning Utgave 156 lungekreft LSL-KRAS G12D musemodell ultralydavbildning 2D-volumkvantifisering tumordannelse B-modus
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