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Skjelett fenotype analyse av en betinget stat3 sletting musemodell

Article DOI: 10.3791/61390-v • 08:42 min • July 3rd, 2020
July 3rd, 2020 •
*1, *2, 1, 1, 1, 1, 3, 1
1Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Science, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology, 2Department of Stomatology, Dalian Medical University, 3The 2nd Dental Center, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology
* These authors contributed equally

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Denne protokollen beskriver en kanonisk metode for å forstå de kritiske genene som kontrollerer osteoklastaktivitet in vivo. Denne metoden bruker en transgen musemodell og noen kanoniske teknikker for å analysere skjelettfenotype.

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Biologi utgave 161 skjelettfenotype benmetabolisme merking osteoklaster STAT3 transgene mus
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