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Koşullu Stat3 Silme Fare Modelinin İskelet Fenotip Analizi

Article DOI: 10.3791/61390-v • 08:42 min • July 3rd, 2020
July 3rd, 2020 •
*1, *2, 1, 1, 1, 1, 3, 1
1Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Science, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology, 2Department of Stomatology, Dalian Medical University, 3The 2nd Dental Center, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology
* These authors contributed equally

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Bu protokol, in vivo osteoklast aktivitesini kontrol eden kritik genleri anlamak için kurallı bir yöntemi açıklar. Bu yöntem, iskelet fenotipini analiz etmek için transgenik bir fare modeli ve bazı kurallı teknikler kullanır.

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Biyoloji Sayı 161 iskelet fenotipi kemik metabolizması etiketleme osteoklastlar STAT3 transgenik fareler
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