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JoVE Journal Medicine
Forudsigelse af amputation ved hjælp af lokale cirkulerende mononukleare stamceller i angioplastikbehandlede patienter med kritisk limbiskæmi
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Forudsigelse af amputation ved hjælp af lokale cirkulerende mononukleare stamceller i angioplastikbehandlede patienter med kritisk limbiskæmi

Article DOI: 10.3791/61503-v • 07:25 min • September 22nd, 2020
September 22nd, 2020 •
1, 1, 1, 1, 1, 1, 1, 2, 2, 2, 2, 3, 3, 3
1Experimental Metabolism and Clinical Research Laboratory, Clinical Research Department, Division of Biomedical Research, Centro Médico Nacional 20 de Noviembre, ISSSTE, 2Vascular Surgery and Angiology Department, Centro Médico Nacional 20 de Noviembre, ISSSTE, 3Regenerative Medicine and Tissue Engineering Laboratory; Coordination of Research, Centro Médico Nacional 20 de Noviembre, ISSSTE

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Amputation af underekstremiteterne kan forekomme selv efter angioplastik af blokerede beholdere i Critical Limb Ischemia (CLI). Mononukleare stamceller afspejler vaskulær reparation. Denne protokol beskriver kvantificeringen af MPC'er fra cirkulation tæt på angioplastik, og dens forhold til endotel dysfunktion og forudsigelse af underekstremitet amputation.

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Medicin Problem 163 flow cytometry MPCs vaskulær blok kritisk lemmer iskæmi angioplastik amputation prognose
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