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Journal / Immunology and Infection / ヒトCRISPR設計CAR-T細胞の製造
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Immunology and Infection

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ヒトCRISPR設計CAR-T細胞の製造
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ヒトCRISPR設計CAR-T細胞の製造

Article DOI: 10.3791/62299-v • 06:33 min • March 15th, 2021
March 15th, 2021 •
*1,2, *1,2, 1,2, 1,2
1Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, 2Parker Institute for Cancer Immunotherapy, University of Pennsylvania
* These authors contributed equally

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ここでは、CRISPR Cas技術を用いてCAR-T細胞を改変する原発ヒトT細胞における遺伝子編集プロトコルを紹介する。

Tags

免疫学と感染症 問題 169 キメラ抗原受容体 (CAR)-T細胞 細胞免疫療法 遺伝子治療 レンチウイルスベクター 遺伝子編集 CRISPR/Cas9 Tリンパ球
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