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Journal / Immunology and Infection / 生产人类CRISPR工程的CAR-T细胞
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Immunology and Infection

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生产人类CRISPR工程的CAR-T细胞

Article DOI: 10.3791/62299-v • 06:33 min • March 15th, 2021
March 15th, 2021 •
*1,2, *1,2, 1,2, 1,2
1Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, 2Parker Institute for Cancer Immunotherapy, University of Pennsylvania
* These authors contributed equally

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在这里，我们提出了一个协议，在原人类T细胞的基因编辑使用CRISPR卡斯技术来修改CAR-T细胞。

Tags

免疫学和感染，第169期，奇美利安抗原受体（CAR）-T细胞，细胞免疫疗法，基因治疗，扁豆载体，基因编辑，CRISPR/Cas9，T淋巴细胞
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