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Journal / Genetics / 演示序列比对以预测跨物种敏感性的工具，用于快速评估蛋白质保存…
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JoVE Journal Genetics
演示序列比对以预测跨物种敏感性的工具，用于快速评估蛋白质保存
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演示序列比对以预测跨物种敏感性的工具，用于快速评估蛋白质保存

Article DOI: 10.3791/63970-v • 16:02 min • February 10th, 2023
February 10th, 2023 •
1, 2, 2, 3, 4, 5, 5, 5, 6
1Office of Research and Development, Center for Computational Toxicology and Exposure, Scientific Computing and Data Curation Division, U.S. Environmental Protection Agency, 2Oak Ridge Institute for Science and Education, 3Swenson College of Science and Engineering, Department of Biology, University of Minnesota Duluth, 4University of Wisconsin-Madison Aquatic Sciences Center, 5General Dynamics Information Technology, Research Triangle Park, 6Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division, U.S. Environmental Protection Agency

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在这里，我们提出了一个协议，以利用最新版本的美国环境保护署序列比对来预测跨物种敏感性（SeqAPASS）工具。该协议演示了在线工具的应用，以快速分析蛋白质保存，并提供可定制且易于解释的跨物种化学敏感性预测。

Tags

遗传学，第192期，跨物种外推，生态毒理学，预测毒理学，新方法，阿片受体，甲状腺素转运蛋白
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