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JoVE Journal Developmental Biology
Fremstilling af 3D decellulariserede matricer fra føtal mus skeletmuskulatur til cellekultur
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Fremstilling af 3D decellulariserede matricer fra føtal mus skeletmuskulatur til cellekultur

Article DOI: 10.3791/65069-v • 07:44 min • March 3rd, 2023
March 3rd, 2023 •
1, 1, 1, 1
1Centre for Ecology, Evolution and Environmental Changes and Global Change & Sustainability Institute, Department of Animal Biology, Faculty of Sciences, University of Lisbon

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I dette arbejde blev en decellulariseringsprotokol optimeret til at opnå decellulariserede matricer af føtal museskeletmuskulatur. C2C12 myoblaster kan kolonisere disse matricer, sprede sig og differentiere. Denne in vitro-model kan bruges til at studere celleadfærd i forbindelse med skeletmuskelsygdomme såsom muskeldystrofier.

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Denne måned i JoVE nummer 193
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