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Fabricação de anisotrópica poliméricas Artificial células apresentadoras para ativação de células T CD8 +

Article DOI: 10.3791/58332-v • 10:16 min • October 12th, 2018
October 12th, 2018 •
*1, *1, 1, 2
1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine
* These authors contributed equally

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Aqui, apresentamos um protocolo para reproducibly e rapidamente gerar biologicamente inspirados, biodegradável articifical apresentadoras de células (aAPC) com tamanho ajustável, forma e apresentação de proteína de superfície de célula T expansão ex vivo ou in vivo .

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Ciências ambientais questão 140 aAPC immunoengineering polímero anisotrópico partícula forma
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